Psychological Stress and the Human Immune System: A Meta-Analytic Study of 30 Years of Inquiry.
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Résumé
The present report meta-analyzes more than 300 empirical articles describing a relationship between psychological stress and parameters of the immune system in human participants. Acute stressors (lasting minutes) were associated with potentially adaptive upregulation of some parameters of natural immunity and downregulation of some functions of specific immunity. Brief naturalistic stressors (such as exams) tended to suppress cellular immunity while preserving humoral immunity. Chronic stressors were associated with suppression of both cellular and humoral measures. Effects of event sequences varied according to the kind of event (trauma vs. loss). Subjective reports of stress generally did not associate with immune change. In some cases, physical vulnerability as a function of age or disease also increased vulnerability to immune change during stressors.
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La notice
- Revue
- Psychological Bulletin
- Thématique
- Stress Responses and Cortisol
- Domaine
- Neuroscience
- Établissements canadiens
- University of British Columbia
- Organismes subventionnaires
- National Institute of Mental Health
- Mots-clés
- StressorImmune systemPsychologyHumoral immunityMeta-analysisImmunityVulnerability (computing)Developmental psychologyCellular immunityImmunologyClinical psychologyMedicineInternal medicineComputer science
- Résumé présent dans OpenAlex
- oui