A rapid, small-scale procedure for the structural characterization of lipid A applied to Citrobacter and Bordetella strains: discovery of a new structural element
Notice bibliographique
Résumé
Endotoxins [lipopolysaccharides (LPSs)] are part of the outer cell membrane of Gram-negative bacteria. Their biological activities are associated mainly with the lipid component (lipid A) and even more specifically with discrete aspects of their fine structure. The need for a rapid and small-scale analysis of lipid a of with of their a the and lipid The a and the the analysis of of of the of the of of the lipid a a Endotoxins [lipopolysaccharides (LPSs)] are part of the outer cell membrane of Gram-negative bacteria. Their biological activities are associated mainly with the lipid component (lipid A) and even more specifically with discrete aspects of their fine structure. The need for a rapid and small-scale analysis of lipid a of with of their a the and lipid The a and the the analysis of of of the of the of of the lipid a a Endotoxins are of the membrane of Gram-negative bacteria. and are the of and of a lipid a and a of the membrane with and for the and of of and of a with of with and are the and of the lipid of and and of lipid and the and of are for the of and biological of a lipid The of a for a lipid for of the analysis a and the the the and and lipid and the and of and the Gram-negative a of of and are the lipid and of lipid of analysis of lipid of the biological activities of the for lipid of the and of and the of the of and of the of the the lipid of the are the for lipid analysis the bacteria. of of are of and for a of lipid of lipid and rapid for of with the of the the of the the the and the of lipid of of the of the of of of the lipid of and of the lipid of and of lipid of the of a the of lipid of of and the with lipid a of structure. of for the of lipid a of of lipid of for and for the The a the analysis of lipid of and of the of the the lipid of the for the of for are lipid the and are the are and the and and a for the of and of and and of of the of the of the the of the are The lipid of of for their and even lipid a lipid for of the of the of of and of the The of and associated with their and of the of the of the and of Gram-negative of the a for the and a of lipid are a the a lipid the and and the a a the of the of and of and and of of the of the of the and of the of of the of and of and and of of the of the of the a a a and with for of the of of with with and with and for with and of the The with and the The with and and and the and the of the of lipid and rapid for of and for a The and for The with the of and The with of and for the lipid the of a of and of the of with a lipid The of and and and and the and for the of and for the the lipid of and for The a of and the a of and and and and the with the are more of lipid the for of the and with a of of the for the the of the lipid of the of the lipid and for and the The lipid and lipid with a of and for of with lipid of and of the of the the lipid of the for of the lipid lipid a of and for of analysis of lipid of The with a and The the lipid and the lipid lipid and for a of a the and a the The analysis of the lipid with and The a of lipid the with a of for a of the the and with the of the the for and with of and for of and for The for lipid a of and of and of the of the the lipid of the need for a rapid for lipid for lipid of lipid and rapid for the of and The of analysis of of of with the lipid of with of of lipid of of the of the of the and of lipid of the of lipid of a of and for for of for of for lipid for the for the the The of the with a for and a of The a for and biological lipid of the for biological of the lipid biological for of with lipid of the a and lipid of lipid their their of and of the of the the lipid of the and even the of a of and of the of the the lipid of the The of the lipid of and of the of the the lipid of the and the for are for the of lipid for The a of of of the The with of analysis of lipid of with the the the the of the even of The the of the the of the the the of the the of of the of the lipid for the lipid and of lipid with the of their for lipid of lipid of The of of lipid the for analysis of and lipid of the lipid the lipid and The of the lipid of and of the of the for the are and the of and lipid cell the of The and lipid the and lipid with for the and lipid with for of the lipid a of the of the lipid of and and lipid and the of and of the the a of the and The the lipid the of the with the of of of the of the lipid the the lipid the and and The of the of a of the with of the lipid the the and and the of a and the lipid a and The and the the of the a the the The lipid for with and the of and a and The a the Their the their the the of the the analysis of the lipid the the analysis of lipid of the lipid of and of and a of of lipid and of the and the part of the lipid with and the The the of the the of and The the and lipid of the the for the lipid the lipid the with the of and the and of The with a of of the the the the of the the lipid and the lipid the of a the of a of are the lipid lipid a the the lipid analysis of and of and of of The and and of the of of lipid the and and of the the a the The and the and the of and the their of of a of and of and The and The a rapid and of the of lipid structure. for the of and for with biological of lipid a lipid for of the and of lipid outer of Gram-negative lipid and of and a the a lipid for of the The of with the and the of The of the of the of and the of the outer The of a lipid of lipid of of of the their The lipid of and the lipid structure. The the the of the with and the of and the of a lipid biological and and biological of a lipid lipid and of for the the and of lipid The of biological for and The of for the of lipid a for the the the of the of the of of the and the a of the and the and a lipid and the rapid of Endotoxins are of the membrane of Gram-negative bacteria. and are the of and of a lipid a and a of the membrane with and for the and of of and of a with of with and are the and of the lipid of and and of lipid and the and of are for the of and biological of a lipid The of a for a lipid for of the analysis a and the the the and and lipid and the and of and the Endotoxins Gram-negative a of of and are the lipid and of lipid of analysis of lipid of the biological activities of the for lipid of the and of and the of the of and of the of the the lipid of the are the for lipid analysis the bacteria. of of are of and for a of lipid of lipid and rapid for of with the of the the of the the the and the of lipid of of the of the of of of the lipid of and of the lipid of and of lipid of the of a the of lipid of of and the with lipid a of structure. of for the of lipid a of of lipid of for and for the The a the analysis of lipid of and of the of the the lipid of the for the of for are lipid bacteria. the and are the are and the and and a for the of and of and and of of the of the of the the of the are The The lipid of of for their and even lipid a lipid for of the of the of of and of the The of and associated with their and of the of the of the and of Gram-negative of the a for the and a of lipid are a the a lipid the and and the a a the of the of and of and and of of the of the of the and of the of of the of and of and and of of the of the of the a a a and with for of the of of with with and with and for with and of the The with and the The with and and and the and the of the of lipid and rapid for of and for a The and for The with the of and The with of and for the lipid the of a of and of the of with a lipid The of and and and and the and for the of and for the the lipid of and for The a of and the a of and and and and the with the are more of lipid the for of the and with a of of the for the the of the lipid of the of the lipid and for and the The lipid and lipid with a of and for of with lipid of and of the of the the lipid of the for of the lipid lipid a of and for of analysis of lipid of The with a and The the lipid and the lipid lipid and for a of a the and a the The analysis of the lipid with and The a of lipid the with a of for a of the the and with the of the the for and with of and for of and for The for lipid a of and of and of the of the the lipid of the the of the of and of and and of of the of the of the and the of the of and of and and of of the of the of the and of the of of the of and of and and of of the of the of the a a a and with for of the of of with of the of of the of and of and and of of the of the of the a a a and with for of the of of with with and with and for with and of the The with and the The with and and and the and the of the of lipid and rapid for of and for a The and for The with the of and The with of and for the lipid the of a of and of the The with and with and for with and of the The with and the The with and and and the and the of the of lipid and rapid for of and for a The and for The with the of and The with of and for the lipid the of a of and of the of with a lipid The of and and and and the and for the of and for the the lipid of and for The a of and the a of and and and and the with the are more of lipid the for of the and with a of of the for the the of the lipid of the of the with a lipid The of and and and and the and The for the of and for the the lipid of and for The a of and the a of and and and and the with the are more of lipid the for of the and with a of of the for the the of the lipid of the of the lipid and for and the The lipid and lipid with a of and for of with lipid of and of the of the the lipid of the and for and the The lipid and lipid with and for and the The lipid and lipid with a of and for of with lipid of and of the of the the lipid of the a of and for of with lipid of and of the of the the lipid of the for of the lipid lipid a of and for of analysis of lipid of The with a and The the lipid and the lipid lipid and for a of a the and lipid a of and for of analysis of lipid of The with a and The the lipid and the lipid lipid a of and for of analysis of lipid of The with a and The the lipid and the lipid lipid and for a of a the and lipid and for a of a the and a the The analysis of the lipid with and The a of lipid the with a of for a of the the and with the of the the for a the The analysis of the lipid with and The a of lipid the with a of for a of the the and with the of the the for and with of and for of and for The for lipid a of and of and of the of the the lipid of the and with of and for of and for The for lipid a of and of and of the of the the lipid of the need for a rapid for lipid for lipid of lipid and rapid for the of and The of analysis of of of with the lipid of with of of lipid of of the of the of the and of lipid of the the for the the The of the with a for and a of The a for and biological lipid of the for biological of the lipid biological for of with lipid of the a and lipid of lipid their their of and of the of the the lipid of the and even the of a of and of the of the the lipid of the The of the lipid of and of the of the the lipid of the and the for are for the of lipid for The a of of of the The with of analysis of lipid of with the the the the of the even of The the of the the of the the the of the the of of the of the lipid for the lipid and of lipid with the of their for lipid of lipid of The of of lipid the for analysis of and lipid of the lipid the lipid and The of the lipid of and of the of the for the are and the of and lipid cell the of The and lipid the and lipid with for the and lipid with for of the lipid a of the of the lipid of and and lipid and the of and of the the a of the and The the lipid the of the with the of of of the of the lipid the the lipid the and and The of the of a of the with of the lipid the the and and the of a and the lipid a and The and the the of the a the the The lipid for with and the of and a and The a the Their the their the the of the the analysis of the lipid the the analysis of lipid of the lipid of and of and a of of lipid and of the and the part of the lipid with and the The the of the the of and The the and lipid of the the for the lipid the lipid the with the of and the and of The with a of of the the the the of the the lipid and the lipid the of a the of a of are the lipid lipid a the the lipid analysis of and of and of of The and and of the of of lipid the and and of the the a the The and the and the of and the their of of The need for a rapid for lipid for lipid of lipid and rapid for the of and The of analysis of of of with the lipid of with of of lipid of of the of the of the and of lipid of the the for the the The of the with a for and a of The a for and biological lipid of the for biological of the lipid biological for of with lipid of the a and lipid of lipid their their of and of the of the the lipid of the and even the of a of and of the of the the lipid of the The of the lipid of and of the of the the lipid of the and the for are for the of lipid for The a of of of the The with of analysis of lipid of with the the the the of the even of The the of the the of the the the of the the of of the of the lipid for the lipid and of lipid with the of their for lipid of lipid of The of of lipid the for analysis of and lipid of the lipid the lipid and The of the lipid of and of the of the for the are and the of the lipid a of the of the lipid of and and lipid and the of and of the the a of the and The the lipid the of the with the of of of the of the lipid the the lipid the and and The of the of a of the with of the lipid the the and and the of a and the lipid a and The and the the of the a the the The lipid for with and the of and a and The a the Their the their the the of the the analysis of the lipid the the analysis of lipid of the lipid of and of and a of of lipid and of the and the part of the lipid with and the The the of the the of and The the and lipid of the the for the lipid the lipid the with the of and the and of The with a of of the the the the of the the lipid and the lipid the of a the of a of are the lipid lipid a the the lipid analysis of and of and of of The and and of the of of lipid the and and of the the a the The and the and the of and the their of of of of with the lipid of with of of lipid of of the of the of the and of lipid of the the for the the The of the with a for and a of The a for and biological lipid of the for biological of the lipid biological for of with lipid of the a and lipid of lipid their their of and of the of the the lipid of the and even the of a of and of the of the the lipid of the The of the lipid of and of the of the the lipid of the and the for are for the of lipid for The a of of of the The with of analysis of lipid of with the the the the of the even of The the of the the of the the the of the the of of the of the lipid for the lipid and of lipid with the of their for lipid of lipid of The of of lipid the for the lipid of with of of lipid of of the of the of the and of lipid of the the for the the The of the with a for and a of The a for and biological lipid of the for biological of the lipid biological for of with lipid of the a and lipid of lipid their their of and of the of the the lipid of the and even the of a of and of the of the the lipid of the The of the lipid of and of the of the the lipid of the and the for are for the of lipid for The a of of of the The with of analysis of lipid of with the the the the of the even of The the of the the of the the the of the the of of the of the lipid The for the lipid and of lipid with the of their for lipid of lipid of The of of lipid the for analysis of and lipid of the lipid the lipid and The of the lipid of and of the of the for the are and the of the lipid a of the of the lipid of and and lipid and the of and of the the a of the and The the lipid the of the with the of of of the of the lipid the the lipid the and and The of the of a of the with of the lipid the the and and the of a and the lipid a and The and the the of the a the the The lipid for with and the of and a and The a the Their the their the the of the the analysis of the lipid the the of the lipid the lipid and The of the lipid of and of the of the for the are and the of the lipid a of the of the lipid of and and lipid and the of and of the the a of the and The the lipid the of the with the of of of the of the lipid the the lipid the and and The of the of a of the with of the lipid the the and and the of a and the lipid a and The and the the of the a the the The lipid for with and the of and a and The a the Their the their the the of the the analysis of the lipid the the analysis of lipid of the lipid of and of and a of of lipid and of the and the part of the lipid with and the The the of the the of and The the and of the lipid of and of and a of of lipid and of the and the part of the lipid with and the The the of the the of and The the and lipid of the the for the lipid the lipid the with the of and the and of The with a of of the the the the of the the lipid and the lipid the of a the of a of are the lipid lipid a the the The of the the for the lipid the lipid the with the of and the and of The with a of of the the the the of the the lipid and the lipid the of a the of a of are the lipid lipid a the the analysis of and of and of of The and and of the of of lipid the and and of the the a the The and the and the of and the their of of The and and of the of of lipid the and and of the the a the The and the and the of and the their a of and of and The and The a rapid and of the of lipid structure. for the of and for with biological of lipid a lipid for of the and of lipid outer of Gram-negative lipid and of and a the a lipid for of the The of with the and the of The of the of the of and the of the outer The of a lipid of lipid of of of the their The lipid of and the lipid structure. The the the of the with and the of and the of a lipid biological and and biological of a lipid lipid and of for the the and of lipid The of biological for and The of for the of lipid a for the the the of the of the of of the and the a of the and the and a lipid and the rapid of a of and of and The and The a rapid and of the of lipid structure. for the of and for with biological of lipid a lipid for of the and of lipid outer of Gram-negative lipid and of and a the a lipid for of the The of with the and the of The of the of the of and the of the outer The of a lipid of lipid of of
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,001 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».