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Movement Disorder Society‐sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS‐UPDRS): Scale presentation and clinimetric testing results

2008· article· en· 7 528 citations· W2140978740 sur OpenAlex· 10.1002/mds.22340

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Résumé

We present a clinimetric assessment of the Movement Disorder Society (MDS)-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS). The MDS-UDPRS Task Force revised and expanded the UPDRS using recommendations from a published critique. The MDS-UPDRS has four parts, namely, I: Non-motor Experiences of Daily Living; II: Motor Experiences of Daily Living; III: Motor Examination; IV: Motor Complications. Twenty questions are completed by the patient/caregiver. Item-specific instructions and an appendix of complementary additional scales are provided. Movement disorder specialists and study coordinators administered the UPDRS (55 items) and MDS-UPDRS (65 items) to 877 English speaking (78% non-Latino Caucasian) patients with Parkinson's disease from 39 sites. We compared the two scales using correlative techniques and factor analysis. The MDS-UPDRS showed high internal consistency (Cronbach's alpha = 0.79-0.93 across parts) and correlated with the original UPDRS (rho = 0.96). MDS-UPDRS across-part correlations ranged from 0.22 to 0.66. Reliable factor structures for each part were obtained (comparative fit index > 0.90 for each part), which support the use of sum scores for each part in preference to a total score of all parts. The combined clinimetric results of this study support the validity of the MDS-UPDRS for rating PD.

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La notice

Revue
Movement Disorders
Thématique
Parkinson's Disease Mechanisms and Treatments
Domaine
Medicine
Établissements canadiens
University of Toronto
Organismes subventionnaires
National Institute of Neurological Disorders and StrokeParkinson's UKGlaxoSmithKlinePfizer
Mots-clés
Rating scaleCronbach's alphaPsychologyMovement disordersPhysical medicine and rehabilitationPhysical therapyParkinson's diseaseActivities of daily livingPsychometricsDiseaseMedicineClinical psychologyPsychiatryDevelopmental psychology
Résumé présent dans OpenAlex
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