Notice bibliographique
Résumé
Exercise-induced anaphylaxis is a rare disorder characterized by the development of a severe allergic response occurring after mild- to-strenuous physical activity. Food-dependent exercise-induced anaphylaxis (FDEIA) comprises 30-50% of all cases of exercise-induced anaphylaxis [ 2 ]. Diagnosis involves careful history and appropriate skin prick testing and food specific IgE levels [ 4 , 6 ]. However, food dependent exercise challenges may be required to confirm the diagnosis [ 6 ]. We describe the case of a 51 year old male, diagnosed with corn dependent exercise anaphylaxis via serial exercise challenges. Case report and literature review. A 51 year old male military pilot described the following symptoms 10 minutes after running on the treadmill: sudden onset palm pruritus, bilateral arm tingling, urticarial rash on his arms and chest, tongue and eyelid swelling, and difficulty speaking/swallowing. He denied wheezing, shortness of breath, gastrointestinal symptoms, or light-headedness. He was self-treated with 50 mg of diphenhydramine and loratadine. His symptoms resolved in 2-3 hours. He had consumed a Shepherd’s Pie approximately 45 minutes prior to exercise. The ingredients included beef, potato, corn, wheat, flour, and Worchestershire sauce. He denied ingestion of ASA/NSAIDS or alcoholic beverages prior to the event. His past medical history was remarkable for hypercholesterolemia and diet-controlled Diabetes Mellitus. He had a history of seasonal allergies for which he was on maintenance allergen immunotherapy. His medications included Crestor, Coenzyme Q10, and a fiber supplement. Physical examination was unremarkable. Skin prick testing to the individual ingredients of the Shepherd’s Pie were negative. IgE levels were positive for corn and wheat, and negative to the other ingredients. Patient was advised a wheat and corn free diet and was able to resume his exercise routine. Subsequently, he underwent serial food dependent exercise challenges. The exercise challenges verified that corn was the culprit food. The patient was advised to stop eating corn, introduce wheat, and resume his regular exercise routine. He had two minor episodes of urticaria with exertion in the following year, confirmed to be from accidental exposure to corn. This case demonstrated that, although wheat is one of the most common triggers of food dependent exercise induced anaphylaxis, corn was the culprit for this patient’s exercise induced symptoms. Food dependent exercise challenges can be time consuming and associated with risks, but yet important to verify the diagnosis when multiple triggers are suspected.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,001 |
| Méta-épidémiologie (sens strict) | 0,001 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,001 | 0,001 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,001 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,003 | 0,001 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».