Prevalence of Maternal Genital Tract Colonization by Group B Streptococcus From Western Province, Taif, Saudi Arabia
Notice bibliographique
Résumé
Background: Group B streptococcus (GBS) or Streptococcus agalactiae are members of the normal flora of the female genital tract. Maternal colonization has been found to be a major risk factor for invasive GBS disease within 6 days of birth. GBS has become the major cause of bacterial infections in the perinatal period, including bacteremia, amnionitis, endometritis, and urinary tract infection in pregnant women as well as sepsis and meningitis in neonates and young infants. Infection of the new born may be acquired by the intra-amniotic route or directly during passage through the birth canal. This study was undertaken to determine the prevalence of GBS colonization in pregnant women attending the antenatal clinic of Al-Hada Armed Forces Hospital in Western province, Taif, Saudi Arabia. This paper was the first data on incidence of GBS in pregnant women at Western province, Taif, Saudi Arabia. Methods: A total of 2,632 pregnant women were screened for GBS colonization between January and December 2014. Standard microbiological methods were used to isolate and identify GBS from vaginal and anorectal swabs obtained from study subjects. An antimicrobial susceptibility test was performed for all GBS isolates according to the criteria of the Clinical and Laboratory Standards Institute (CLSI) by disk diffusion method. Results: A total of 632 out of 2,632 (24%) pregnant women were colonized by GBS. Statistically significant association was observed for GBS colonization with any of socio-demographic characteristics of the study subjects including age, occupation, number of antenatal clinic visits, and type of gravida. All GBS strains were susceptible to penicillin, ampicillin, vancomycin and gentamicin, erythromycin, tetracycline, ceftriaxone, chloramphenicol, ciprofloxacin, clindamycin, and norfloxacin. Resistance was observed in some strains against clindamycin (0.18%). The data from the present study showed that incidence of GBS in Saudi pregnant women increased rapidly. These results are the first record of the database in Saudi Arabia at western province with high prevalence of GBS in pregnant women. Conclusion: This study showed that prevalence of GBS colonization was 24% among the study subjects. The finding of this study was comparable with findings reported from developed and developing countries. However, further epidemiological investigations should be done in different parts of the country (all provinces) in order to know the actual GBS colonization rate in pregnant women and to consider the use of intrapartum antibiotics prophylaxis for prevention of early onset GBS-neonatal diseases, considering the accelerated demand for reducing neonatal morbidity and mortality due to GBS. J Clin Gynecol Obstet. 2015;4(3):258-264 doi: http://dx.doi.org/10.14740/jcgo341w
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Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,001 | 0,005 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».