Re: Non‐visualization of the cavum septi pellucidi is not synonymous with agenesis of the corpus callosum. G. Malinger, D. Lev, M. Oren and T. Lerman‐Sagie. <i>Ultrasound Obstet Gynecol</i> 2012; 40: 165–170.
Notice bibliographique
Résumé
The cavum septi pellucidi (CSP) et Vergae is the hypoechoic fluid-containing rectangular space between the as yet unfused laminae of the septum pellucidum on standard axial views of the head until septal fusion occurs, typically in the third trimester, forming the single septum pellucidum. The utility and importance of CSP identification at prenatal ultrasound as a marker for normal development of midline structures including the corpus callosum has been affirmed by several investigators1. Failure to demonstrate the normal CSP at the mid-trimester anatomy scan should trigger detailed assessment of the brain and other anatomy and consideration of counseling and further investigations. What remains as a clinical problem is the significance of alterations in the appearance of the CSP, including unexpectedly large or small size and alteration in the appearance of its contents. In this issue of the Journal, Malinger and colleagues have reviewed the unusual occurrence of failure to see fluid in the CSP, in fetuses evaluated from 22 to 35 gestational weeks. It is reassuring that in most cases the finding was isolated and followed by normal outcome. Nonetheless, a few cases had problems, reaffirming the approach that any deviation from normal appearance should lead to further assessment. The embryology of the corpus callosum (CC) and CSP is complex2, 3. An issue that Malinger et al. raise is the range of normal sonographic appearances of the septa, CSP and fornices around the time of their initial formation in early pregnancy. Embryological reviews suggest that even up to 17–20 weeks the septal walls may be quite thick and leave little space for fluid2, 4. In contrast, at ultrasound, the CSP is described as a clear box with thin walls (septa) that become visible in some fetuses as early as 15 weeks and in all normal fetuses by 16–18 weeks5. Clarification of the normal early developmental sonographic appearance of this region is especially relevant today, with the increased emphasis on early anatomical assessment using very high-resolution transvaginal probes and multiple views (coronal and sagittal). Until clarification is achieved, caution should be exercised regarding counseling related to suspected CSP/CC variations prior to 18 gestational weeks. It is important to remember that as new and ever more sophisticated transducers and image processing are introduced, ‘new’ unexpected findings will be observed. These should be reported and managed with caution until their significance is established. A. Toi*, * University of Toronto, Princess Margaret Hospital, 610 University Avenue, Room 4-833, Toronto, Canada, M5G 2M9
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,012 |
| Méta-épidémiologie (sens strict) | 0,001 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,000 |
| Bibliométrie | 0,000 | 0,001 |
| Études des sciences et des technologies | 0,000 | 0,001 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,001 | 0,000 |
| Intégrité de la recherche | 0,001 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».