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Enregistrement W2223551915

Follower load influences the kinematics and kinetics of cervical spine buckling during simulated head first impact: an ex vivo study

2012· article· en· W2223551915 sur OpenAlexaboutno aff
Christopher R. Dennison, Amy Saari, Qingan Zhu, Sacha B. Nelson, Philip L. Morley, Eyal Itshayek, Thomas R. Oxland, Peter A. Cripton

Notice bibliographique

Revuenon disponible
Typearticle
Langueen
DomaineMedicine
ThématiqueSpinal Fractures and Fixation Techniques
Établissements canadiensnon disponible
Organismes subventionnairesnon disponible
Mots-clésBiomechanicsCadaverMedicineKinematicsWhiplashEx vivoCervical spineAnatomyCadaveric spasmSurgeryPoison controlIn vivoPhysics
DOInon disponible

Résumé

récupéré en direct d'OpenAlex

DURING SIMULATED HEAD FIRST IMPACT: AN EX VIVO STUDY Christopher R. Dennison, Amy Saari, Qingan Zhu , Tim Nelson, , Philip Morley, Eyal Itshayek, Tom Oxland and Peter A. Cripton Orthopaedic and Injury Biomechanics Group; Department of Mechanical Engineering Department of Orthopaedics; International Collaboration on Repair Discoveries University of British Columbia Vancouver, Canada; Department of Neurosurgery. Hadassah Hebrew University Hospital. Jerusalem. Israel INTRODUCTION Cervical spine injuries result in significant financial cost to the injured and society. Spinal cord injuries can lead to severe disability and death. Understanding of the biomechanics of these injuries is based on decades of study that consider in vivo and ex vivo axial compression. Early biomechanical studies used whole cadavers but lacked measurement of cervical kinetics and kinematics because the neck was surrounded by musculature. More recent studies use isolated cervical spine-head complexes that allow measurement of cervical kinetics and kinematics because musculature is removed. Both whole cadaver and spine-head studies suggest that, during head first impact, the cervical spine buckles as the head impact moves it toward the relatively more massive torso and further that the type of buckling and resulting injuries may be correlated [1]. Some impact studies describe cables tethered to cervical anatomy to simulate the role of neck musculature in controlling neck posture and have succesfuly recreated clinically-observed injuries. However, these cables do not recreate lines of action of compressive follower loads that neck musculature supplies in vivo and that has been shown through recent modeling to significantly increase neck injury risk [2]. For quasi-static loading, ex vivo experimental work has shown that compressive follower loads (guided at each level) increase the compressive loads at which buckling occurs but without follower loads the isolated cervical spine could not even support the weight of the head[3]. Due to this evidence, we hypothesize that it is important to simulate in vivo compressive follower load in ex vivo experiments for headfirst impact. Moreover, we hypothesize that buckling in past ex vivo impact experiments [1] may be due to absence of any approach to simulate musculature that is present in vivo. The objective of this work was to compare the kinematics/kinetics of buckling, during head-first impact, of isolated cervical head/neck complexes instrumented with follower load to those without preload. METHODS We simulated head-first impact of cervical spine-head complexes (n=12) using a drop-tower. Six complexes (Occ.T1) were instrumented with follower load (FL group), while six were not (NFL group). Occiputs of all specimens were fixed to a biofidelic surrogate head and T1 was encased in a mounting cup. The metrics relevant to buckling that are reported in this abstract are: impact speed; time to neck buckle; the vertebral levels at which the neck buckles; and the total angular divergence at the levels at which the neck buckled. The criterion to determine buckling and vertebral level of buckling was failure of the neck to support compressive force while C7 continued to translate toward the head and divergence of angular rotation across any two or three vertebral levels as indicated by opposing rotation direction that was greater than 2 degrees. RESULTS The mean impact speeds were 2.8 m/s (NFL) and 2.9 m/s (FL). There was a significant difference (p=0.009) in time to buckle between the NFL and FL group, which had means of 4.9 msec and 2.5 msec, respectively. For the FL group, 3/6 of specimens buckled across C4/5 (Fig. 1), 2/6 across C3/4 and 1/6 across C2/3. For the NFL group, buckling in 5/6 specimens involved C4 rotation being nominally zero while C3 and C5 had negative and positive rotation (sign convention in Fig. 1), respectively. The remaining NFL specimen buckled (opposing rotations) across C3/4. The FL specimens (avg. 5 degrees) had significantly smaller (p=0.002) rotations at buckle than the NFL (avg. 20 degrees). All specimens exhibited overall hyperextension across the spine (Fig. 1).

Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.

Comment cette classification a été obtenuedéplier

Prédiction machine sur la base complète

Imitation des enseignants

Ni prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.

score de la tête « metaresearch » (Codex)0,000
score de la tête « metaresearch » (Gemma)0,001
Version: metacan-v3-hybrid-931329e0061cStatut de validation: machine_predicted_unvalidated
Catégories candidatesaucune
Catégories consensuellesaucune
DomaineSignal candidat: aucune · Signal consensuel: aucune
Devis d'étudeSignal candidat: Expérimental (laboratoire) · Signal consensuel: Expérimental (laboratoire)
GenreSignal candidat: Empirique · Signal consensuel: Empirique
Score de désaccord entre enseignants0,004
Score d'incertitude au seuil0,012

Scores du classifieur distillé par catégorie (deux têtes)

CatégorieCodexGemma
Métarecherche0,0000,001
Méta-épidémiologie (sens strict)0,0000,000
Méta-épidémiologie (sens large)0,0000,000
Bibliométrie0,0000,000
Études des sciences et des technologies0,0000,000
Communication savante0,0000,000
Science ouverte0,0000,000
Intégrité de la recherche0,0010,000
Charge utile insuffisante (le modèle a refusé de juger)0,0040,001

Scores machine (provisoires)

Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.

Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.

Tête enseignante Opus0,025
Tête enseignante GPT0,361
Écart entre enseignants0,336 · la distance entre les deux têtes enseignantes sur ce seul travail
Statut de validationscore_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découle

Classification

machine, non validée

Prédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.

Les modèles n’ont appliqué aucune catégorie : rien dans la taxonomie ne correspondait à ce travail.
Devis d'étudeExpérimental (laboratoire)
Domainenon disponible
GenreEmpirique

Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».

En bref

Citations0
Publié2012
Routes d'admission1
Résumé présentoui

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