Science AMA Series: We recently published a manuscript that showed modern humans had sex with Neandertals approximately 100,000 years ago, which is ~50,000 years earlier than previously known human/Nea
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Notice bibliographique
Résumé
Hi Reddit! The publication can be found here: http://www.nature.com/nature/journal/vaop/ncurrent/full/nature16544.html. Who we are: Co-authors Martin Kuhlwilm, Bence Viola, Ilan Gronau, Melissa Hubisz, Adam Siepel, and Sergi Castellano. Martin Kuhlwilm is a geneticist, currently working at the UPF in Barcelona and previously at the Max Planck Institute in Leipzig. He studies modern human, Neandertal and great ape genomes, to understand what is special for each group and which evolutionary patterns can be found. He also studies migration patterns among hominin groups and great ape populations. Bence Viola is a paleoanthropologist at the University of Toronto. His main interest is how different hominin groups interacted biologically and culturally in the Upper Pleistocene (the last 200 000 years). He combines data from archaeology, morphology and genetics to better understand how the contacts between Neanderthals, Denisovans and modern humans happened. He mostly works in Central Asia and Central Europe, two areas where contacts between modern and archaic humans are thought to have taken place. Sergi Castellano, from the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, focuses on understanding the role of essential micronutrients, with particular emphasis on selenium, in the adaptation of human metabolism to the different environments encountered by archaic and modern humans as they migrated around the world. His group is also interested in the population history of these humans as it relates to their interbreeding and exchange of genes that facilitate adaptation to new environments. Melissa, Ilan, and Adam used to work together in the Siepel lab at Cornell University, and continue to work together from a distance. Currently, Ilan is a faculty member in Computer Science at the Interdisciplinary Center in Herzliya, Israel. Adam is a professor at the Simons Center for Quantitative Biology at the Cold Spring Harbor Laboratory on Long Island, New York. Melissa is a graduate student in Computational Biology at Cornell. They are especially interested in applying probabilistic models to genomic data to learn about human evolution and population genetics. Ask us anything! (Except whether “Neanderthal” should be spelled with an ‘h’.. we don’t know!) Update: Thanks everyone for having us! Hope we were able to answer some of your questions. We’re signing off now!
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,004 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,001 | 0,001 |
| Méta-épidémiologie (sens large) | 0,002 | 0,000 |
| Bibliométrie | 0,001 | 0,001 |
| Études des sciences et des technologies | 0,007 | 0,001 |
| Communication savante | 0,000 | 0,001 |
| Science ouverte | 0,003 | 0,002 |
| Intégrité de la recherche | 0,001 | 0,002 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,010 | 0,002 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découle