Variation in mammographic density during menstrual cycle
Notice bibliographique
Résumé
A54 Background: The sensitivity of mammography for cancer detection is less in women aged 40-49 compared to older women, due in part to more extensive mammographic density in younger women. To improve the quality of screening it has been suggested that premenopausal women to be examined in the follicular phase of the menstrual cycle, when density is thought to be less extensive than in the luteal phase. We have examined the extent to which mammographic density and dense area vary according to the menstrual cycle. > Methods: Premenopausal women aged 40-49 with regular menstrual cycles, without a history of breast disease, and who had mammograms at Sunnybrook/Women’s College or Mount Sinai Hospitals participated in the study. We measured percent breast density, breast area, and dense area using the Cumulus software. Dates of the first day of the last and next menstrual cycles (NMC) were determined by follow-up phone calls. To determine the time in the cycle when the mammogram was taken, the interval between mammogram date and the date of the start of NMC was calculated, and divided into 4 intervals: interval 1 (>21 days before NMC), interval 2 (15-21 days before NMC), interval 3 (8-14 days before NMC) and Interval-4 (≤7 days before NMC). > Results: The total number of subjects included in the analysis was 419: 77 in interval 1, 109 in interval 2, 105 in interval 3 and 128 in interval 4. The least square means of dense area after adjusting for age, BMI, breast thickness and mammography machine characteristics ( KV, MAS and Pressure), were 51.4 cm 2 , 49.6 cm 2 , 50.7 cm 2 and 55.5 cm 2 during intervals 1-4 respectively, however, the results were not statistically significant. The adjusted least square means of percent density were 41.7%, 39.5%, 40.5% and 41.9% during intervals 1-4 respectively; the results were not statistically significant. There were no significant variations between different intervals with regards to mammographic density after adjusting for age, BMI, breast thickness and mammography machine characteristics, such as KV, MAS and Pressure. > Conclusion: There was no difference in mammographic density in relation to the time of mammography after adjusting for machine parameters. Data do not support the suggestion that premenopausal women would benefit from having mammographic examination in the follicular phase of menstrual cycle.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,002 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».