664Influenza Vaccination in Chronically Ill Children: Taking a Closer Look at LAIV
Notice bibliographique
Résumé
Background. Children with underlying chronic conditions are sub-optimally vaccinated against influenza, even if influenza vaccines (IV) are publicly funded. Since 2012, the province of Quebec has recommended live-attenuated IV (LAIV) as the preferred vaccine for children with non-immunocompromising conditions. For a second consecutive year, an influenza vaccination clinic was set up in our pediatric tertiary care hospital. We aimed to compare this clinic's results to last year's and evaluate patients' preference for LAIV vs trivalent inactivated IV (TIV). Methods. Between October 15 and December 24 of each year (2012 and 2013), a vaccination clinic was opened weekdays during working hours and staffed with vaccine nurses. TIV and LAIV were available. Parents were asked to fill a pre-piloted questionnaire. Descriptive statistics were used. Results. During both years, we reached 630 patients with chronic illnesses accounting for 9% of the total outpatient visits for that time of year. In 2013, 264 (44%) were between 2 and 9 years, 257 (43%) were aged 9 to 18 years and 75 (13%) of vaccinated patients were immunosuppressed. Of the 623 participants for whom the information was available, 378 (61%) had received their IV in the previous year and in 49% (172/348), had received it in our vaccination clinic. For 122 of 603 parents who answered (20%), the presence of this vaccination clinic was instrumental in their child receiving their IV. In 2012, 437 of 588 patients aged 2 years and over (74%) were vaccinated with LAIV, compared to 348 of 512 (68%) this year (p = 0.02). These represented 79% of LAIV eligible children (n = 442). Of 360 patients previously vaccinated, 103 (29%) had received LAIV the year before and 88% chose to be vaccinated again with LAIV this year. LAIV was preferred by caregivers (n = 341) because it was perceived as less painful (49%), no needle was involved (41%) and in 42% because of their physician's recommendation. Additionally, 487 household members were vaccinated in 2013. Conclusion. Yearly influenza vaccination coverage in children with chronic illnesses can be improved with a vaccination clinic on site at a tertiary centre. Household members are also reached through this strategy. When LAIV is not contra-indicated, it remains caregivers' and patients' preferred vaccine. Disclosures. All authors: No reported disclosures.
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Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,001 | 0,003 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,001 | 0,000 |
| Communication savante | 0,001 | 0,001 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,001 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,002 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».