PTH-077 Fertility and pregnancy related misconceptions in female patients with inflammatory bowel disease
Notice bibliographique
Résumé
Introduction Reproductive issues in patients with inflammatory bowel disease (IBD) have been shown to be inadequately addressed by clinicians. Patients appear to opt for voluntary childlessness due to misconceptions about fertility and pregnancy. Method Female IBD patients were prospectively recruited from 5 different European centres. They were interviewed through the use of a questionnaire. Results 233 patients were recruited (mean age 40; SD±11.9). The mean age at diagnosis was 31.4 years (SD±11.2). 85.5% patients with ulcerative colitis (UC) had a Montreal classification of E2 or E3. Crohn’s disease (CD) patients predominantly (64.7%) had a non-stricturing and non-penetrating phenotype. Only 57.9% of patients were counselled on IBD and fertility (gastroenterologists 46.8%; gynaecologists 7.30%). 27.5% had admitted to considering voluntary childlessness. This correlated with lack of counselling delivered by health care professionals (coefficient 1.147; p < 0.003). Reasons included: (i) fear of harm from the disease to the baby (52.8%); (ii) fear of harm from medications to the baby (61.4%); (iii) fear of passing on IBD to the baby (57.9%); (iv) fear of having a complicated pregnancy (51.5%); (v) being incapable of taking care of their child after birth (8.6%). 19.7% expressed fear of infertility following the diagnosis of IBD. 8.2% were aware that the mode of delivery could be influenced by IBD. 15.5% and 36.5% knew that surgery could influence fertility and mode of delivery respectively. Regarding IBD medications during pregnancy: (i) 15.0% thought that all medications should be stopped; (ii) 12.0% believed that some medications should be stopped; (iii) 63.1% were unsure about what to do with medications. 1.7% of patients stopped medications without consultation with clinical teams. 26.6% of patients were uncertain if patients with IBD could breast feed. 37.0% said that they could not. 47.0% thought that females with IBD could not breastfeed due to medications crossing into the breast milk. 15.9% were counselled to undergo regular pap smears. 61.8% received information about the HPV vaccine. Conclusion The effects of inadequate fertility counselling in patients with IBD in Europe might contribute to the high levels of voluntary childlessness. A number of misconceptions about pregnancy and delivery exist. This study highlights the need to improve care for this cohort of patients through the development of a multidisciplinary team management. Further studies might allow us to evaluate the most effective way of delivering improved support for these patients. Disclosure of interest None Declared.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,001 | 0,006 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,001 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,001 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,005 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».