Update in Pulmonary Medicine: Evidence Published in 2015

Updates3 May 2016Update in Pulmonary Medicine: Evidence Published in 2015Christopher Howard, MD and Kalpalatha Guntupalli, MDChristopher Howard, MDFrom Baylor College of Medicine, Houston, Texas.Search for more papers by this author and Kalpalatha Guntupalli, MDFrom Baylor College of Medicine, Houston, Texas.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/M16-0225 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail This report summarizes some of the most relevant studies in pulmonary medicine published in 2015. Selected papers were among the most frequently accessed and highest-ranked articles from ACP JournalWise and ACP Journal Club. For patients with chronic obstructive pulmonary disease (COPD), there is now more clarity and consensus about the benefits of pulmonary rehabilitation. Furthermore, for a certain phenotype of patient with COPD who has eosinophilia, therapy with inhaled corticosteroids (ICS), alone or with long-acting β2-agonists (LABAs), seems to have a particularly important effect in the reduction of acute exacerbations. In addition, for the first time, there are published guidelines ...References1. Spruit MA, Singh SJ, Garvey C, ZuWallack R, Nici L, Rochester C, et al; ATS/ERS Task Force on Pulmonary Rehabilitation. An official American Thoracic Society/European Respiratory Society statement: key concepts and advances in pulmonary rehabilitation. Am J Respir Crit Care Med. 2013;188:e13-64. [PMID: 24127811] doi:10.1164/rccm.201309-1634ST CrossrefMedlineGoogle Scholar2. Criner GJ, Bourbeau J, Diekemper RL, Ouellette DR, Goodridge D, Hernandez P, et al. Prevention of acute exacerbations of COPD: American College of Chest Physicians and Canadian Thoracic Society Guideline. Chest. 2015;147:894-942. [PMID: 25321320] doi:10.1378/chest.14-1676 CrossrefMedlineGoogle Scholar3. Singh S, Loke YK. An overview of the benefits and drawbacks of inhaled corticosteroids in chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2010;5:189-95. [PMID: 20714372] doi:10.2147/COPD.S6942 CrossrefMedlineGoogle Scholar4. Jorenby DE, Hays JT, Rigotti NA, Azoulay S, Watsky EJ, Williams KE, et al; Varenicline Phase 3 Study Group. Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial. JAMA. 2006;296:56-63. [PMID: 16820547] CrossrefMedlineGoogle Scholar5. Wewers ME, Stillman FA, Hartman AM, Shopland DR. Distribution of daily smokers by stage of change: Current Population Survey results. Prev Med. 2003;36:710-20. [PMID: 12744915] CrossrefMedlineGoogle Scholar6. Fiore MC, Jaén CR, Baker TB, Bailey WC, Benowitz NL, Curry SJ, et al. Treating Tobacco Use and Dependence: 2008 Update. Clinical practice guideline. Rockville, MD: U.S. Department of Health and Human Services, Public Health Service; 2008. Google Scholar7. Kerstjens HA, Disse B, Schröder-Babo W, Bantje TA, Gahlemann M, Sigmund R, et al. Tiotropium improves lung function in patients with severe uncontrolled asthma: a randomized controlled trial. J Allergy Clin Immunol. 2011;128:308-14. [PMID: 21636120] doi:10.1016/j.jaci.2011.04.039 CrossrefMedlineGoogle Scholar8. Kerstjens HA, Engel M, Dahl R, Paggiaro P, Beck E, Vandewalker M, et al. Tiotropium in asthma poorly controlled with standard combination therapy. N Engl J Med. 2012;367:1198-207. [PMID: 22938706] CrossrefMedlineGoogle Scholar9. Sforza E, Roche F. Sleep apnea syndrome and cognition. Front Neurol. 2012;3:87. [PMID: 22661967] doi:10.3389/fneur.2012.00087 CrossrefMedlineGoogle Scholar10. McMillan A, Bratton DJ, Faria R, Laskawiec-Szkonter M, Griffin S, Davies RJ, et al; PREDICT Investigators. Continuous positive airway pressure in older people with obstructive sleep apnoea syndrome (PREDICT): a 12-month, multicentre, randomised trial. Lancet Respir Med. 2014;2:804-12. [PMID: 25172769] doi:10.1016/S2213-2600(14)70172-9 CrossrefMedlineGoogle Scholar11. The Acute Respiratory Distress Syndrome Network. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med. 2000;342:1301-8. [PMID: 10793162] CrossrefMedlineGoogle Scholar12. Putensen C, Theuerkauf N, Zinserling J, Wrigge H, Pelosi P. Meta-analysis: ventilation strategies and outcomes of the acute respiratory distress syndrome and acute lung injury. Ann Intern Med. 2009;151:566-76. [PMID: 19841457] LinkGoogle Scholar13. Checkley W, Brower R, Korpak A, Thompson BT; Acute Respiratory Distress Syndrome Network Investigators. Effects of a clinical trial on mechanical ventilation practices in patients with acute lung injury. Am J Respir Crit Care Med. 2008;177:1215-22. [PMID: 18356562] doi:10.1164/rccm.200709-1424OC CrossrefMedlineGoogle Scholar14. Blum CA, Nigro N, Briel M, Schuetz P, Ullmer E, Suter-Widmer I, et al. Adjunct prednisone therapy for patients with community-acquired pneumonia: a multicentre, double-blind, randomised, placebo-controlled trial. Lancet. 2015;385:1511-8. [PMID: 25608756] doi:10.1016/S0140-6736(14)62447-8 CrossrefMedlineGoogle Scholar15. ADRENAL. ADjunctive corticosteroid trEatment IN criticAlly ilL Patients with Septic Shock [clinical trial]. ClinicalTrials.gov: NCT01448109. Accessed at https://clinicaltrials.gov/ct2/show/NCT01448109 on 29 February 2016. Google Scholar16. ESCAPe. Extended Steroid in CAP(e) [clinical trial]. VA Clinical Study Protocol #574. ClinicalTrials.gov: NCT01283009. Accessed at https://clinicaltrials.gov/ct2/show/NCT01283009 on 29 February 2016. Google Scholar Author, Article, and Disclosure InformationAffiliations: From Baylor College of Medicine, Houston, Texas.Disclosures: Dr. Guntupalli reports grants from Leading BioSciences, Vanderbilt University, AstraZeneca, and National Institutes of Health, as well as other (advisory work) with the Lattice Group outside the submitted work. Dr. Howard has disclosed no conflicts of interest. Disclosures can also be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M16-0225.Editors' Disclosures: Christine Laine, MD, MPH, Editor in Chief, reports that she has no financial relationships or interests to disclose. Darren B. Taichman, MD, PhD, Executive Deputy Editor, reports that he has no financial relationships or interests to disclose. Cynthia D. Mulrow, MD, MSc, Senior Deputy Editor, reports that she has no relationships or interests to disclose. Deborah Cotton, MD, MPH, Deputy Editor, reports that she has no financial relationships or interest to disclose. Jaya K. Rao, MD, MHS, Deputy Editor, reports that she has stock holdings/options in Eli Lilly and Pfizer. Sankey V. Williams, MD, Deputy Editor, reports that he has no financial relationships or interests to disclose. Catharine B. Stack, PhD, MS, Deputy Editor for Statistics, reports that she has stock holdings in Pfizer.Corresponding Author: Kalpalatha Guntupalli, MD, Baylor College of Medicine, 6620 Main Street, Houston, TX 77030; e-mail, [email protected]edu.Current Author Addresses: Drs. Howard and Guntupalli: Baylor College of Medicine, 6620 Main Street, Houston, TX 77030.Author Contributions: Conception and design: C. Howard, K. Guntupalli.Drafting of the article: C. Howard, K. Guntupalli.Critical revision of the article for important intellectual content: K. Guntupalli.Final approval of the article: C. Howard, K. Guntupalli.Collection and assembly of data: C. Howard, K. Guntupalli. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 3 May 2016Volume 164, Issue 9Page: W55-W60KeywordsAcute respiratory distress syndromeAsthmaContinuous positive airway pressureEosinophilsIntensive care unitsMortalityObstructive sleep apneaPneumoniaSteroidsTidal volume ePublished: 3 May 2016 Issue Published: 3 May 2016 Copyright & PermissionsCopyright © 2016 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...

Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.