A Randomized Controlled Trial of Spiritually-Focused Meditation In Patients Newly Diagnosed with Acute Leukemia.
Notice bibliographique
Résumé
Abstract Abstract 1519 Cancer patients view religion and/or spirituality as personally important and addressing the spiritual needs of cancer patients is a critical component of cancer care. Evidence suggests that secularized forms of meditation improve quality of life (QOL) for cancer patients. Integrating patient's religious or spiritual beliefs into meditations may augment these effects on QOL. We conducted a randomized controlled trial evaluating the effects of spiritually-focused meditation for patients admitted at our institutions with newly diagnosed acute myeloid leukemia or acute lymphocytic leukemia. The study was approved by the Institutional Review Board. Ninety-one acute leukemia patients enrolled in the study and were randomly assigned to: usual care control (UCC), spiritually-focused meditation (SpM), or secularly-focused meditation (SM). During five 1-hour intervention sessions delivered between admission and discharge, participants were taught secular meditation (SM condition) or spiritually framed meditation (SpM condition). All participants completed outcome measures at the beginning of the study, at discharge, two-, four-, and six-months later. Outcome measures included: The Center for Epidemiological Studies-Depression Scale (CES-D), The McGill Quality of Life Scale (MQOL), Positive and Negative Affective States Scale (PANAS Positive and PANAS Negative affect), The Functional Assessment of Cancer Therapy-Physical Well-being (FACT-Ph) subscale, Patient Reported Pain Score, and the use of narcotic and non-narcotic analgesics. Forty-two participants (17 UCC, 13 SpM, 12 SM) who remained in the study through the follow-up period were assessable for analysis. The levels of depression for SpM (p = 0.04) and SM (p = 0.001) decreased significantly across assessment points while levels of depression for UCC remained constant. There was interaction of time and FACT-Ph (F (8, 156)=2.01; p= 0.05). Post hoc analyses indicated that this was accounted for by differences between the UCC and SpM participants at the 6 month follow-up. SpM participants reported more physical health symptoms than the UCC participants even though there were no significant differences in complete remission rates among the three groups. There was a significant group effect for PANAS negative affect in that the SM participants (X= 2.15) reported more negative affect than the UCC participants (X = 1.66), averaged across assessment points. There were no other interactive effects for any of the other outcome measures. The use of narcotic and non-narcotic analgesics and Pain Scores were similar across all three groups. Minutes of meditation or relaxation practice was related to lower CES-D scores (p = 0.02) at admission prior to intervention participation, and was related to greater perceived social support as assessed by the MQOL (p = 0.05) at discharge. Frequency of practice was associated with MQOL Existential subscale (p = 0.05), MQOL psychological subscale (p = 0.05), CES-D (p =0.01), and PANAS Positive (p < .01), at the 4 month assessment. In conclusion, these results suggest that meditation programs, secularly or spiritually framed, are beneficial for acute leukemia patients who are hospitalized for initial induction chemotherapy. Disclosures: No relevant conflicts of interest to declare.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,002 | 0,003 |
| Méta-épidémiologie (sens strict) | 0,001 | 0,001 |
| Méta-épidémiologie (sens large) | 0,004 | 0,002 |
| Bibliométrie | 0,001 | 0,001 |
| Études des sciences et des technologies | 0,001 | 0,001 |
| Communication savante | 0,001 | 0,001 |
| Science ouverte | 0,001 | 0,001 |
| Intégrité de la recherche | 0,002 | 0,003 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,012 | 0,001 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».