An assessment of the patterns and severity of diabetic neuropathy using the modified - Toronto Clinical Neuropathy Score in recently detected diabetics
Notice bibliographique
Résumé
Introduction: Diabetic neuropathy is among the commonest vascular complication of diabetes mellitus. Even individuals with pre-diabetes are at risk of developing diabetic neuropathy (DN). Over 50% of individuals with DN are asymptomatic, keeping them at a higher risk of developing diabetic foot. The study aimed to ascertain the patterns and severity of diabetic neuropathy among patients with recently detected diabetes mellitus, using the ‘modified -Toronto Clinical Neuropathy Score’ (m-TCNS). Materials & methods: This prospective observational study was done on 50 patients with diabetes of less than 1 year duration. Patients who fulfilled the selection criteria were recruited to the study after obtaining a written informed consent. After obtaining details of their medical history, clinical examination and investigations, patients underwent m-TCNS. Laboratory tests included sugar levels, HbA1c and urine albumin. The incidence, severity and patterns of diabetic neuropathy (DN) and its correlation to the duration, diabetes control, presence of retinopathy and albuminuria were analyzed by descriptive statistics, Chi-square test and ‘t’ test. Results: Among the 50 patients, there were 18 males and 32 females with a mean (±SD) age of 56.44 (+10. 82) years. Among them, 29 patients were new to treatment for diabetes. The average random blood sugar (RBS) and glycated hemoglobin (HbA1c) were 249.92 (±126.63) mg/dl and 10.532 (±10.64) gm% respectively. Only 46% patients had symptoms and 34% had signs of diabetic neuropathy. Pain being the commonest symptom (24%) and loss of vibration sense the most frequent sign (26%) in these patients. Features of diabetic retinopathy and albuminuria were present in 6/50 (12%) and 20/50 (40%) patients respectively. The presence or severity of neuropathic signs or symptoms had no statistically significant correlation to their glycemic control. There was a significant correlation of presence of neuropathy with albuminuria and retinopathy. Conclusion: The study establishes the use of m-TCNS as a simple and good screening tool to detect diabetic neuropathy. Pain and loss of vibration sense were the most common symptom and sign in DN. The severity of neuropathy was mild in this study, but had a significant correlation with other microvascular complications. We recommend all newly detected patients with diabetes to undergo screening tests for its microvascular complications.
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Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,004 | 0,002 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,001 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,001 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».