MP05-10 UPDATE ON THE LARGEST CANADIAN RARP EXPERIENCE: ONCOLOGICAL AND FUNCTIONAL OUTCOMES OF 1034 RARP CASES WITH 6-YEAR FOLLOW-UP
Notice bibliographique
Résumé
You have accessJournal of UrologyProstate Cancer: Localized: Surgical Therapy I1 Apr 2018MP05-10 UPDATE ON THE LARGEST CANADIAN RARP EXPERIENCE: ONCOLOGICAL AND FUNCTIONAL OUTCOMES OF 1034 RARP CASES WITH 6-YEAR FOLLOW-UP Côme Tholomier, Félix Couture, Marc Zanaty, Khaled Ajib, Assaad El-Hakim, and Kevin C. Zorn Côme TholomierCôme Tholomier More articles by this author , Félix CoutureFélix Couture More articles by this author , Marc ZanatyMarc Zanaty More articles by this author , Khaled AjibKhaled Ajib More articles by this author , Assaad El-HakimAssaad El-Hakim More articles by this author , and Kevin C. ZornKevin C. Zorn More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.02.181AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES RARP (robotic-assisted radical prostatectomy) is now the predominant surgical approach to treat localized prostate cancer. However, there is still limited Canadian data on its outcomes. We herein update the largest RARP experience in Canada, focusing on oncological and functional outcomes. METHODS Prospective data from 1034 cases of RARP performed by two staff surgeons (KCZ, AE) at a single academic center were collected from October 2016 to June 2017. Pre-operative characteristics and post-operative surgical, pathological, functional and oncological outcomes were assessed up to 72 months postoperative. RESULTS Median follow-up (interquartile range) was 30 months (12-48). D’Amico risk distribution was 26.1% low, 59.8% intermediate and 14.1% high-risk. Median operative time was 170 minutes (145-200), blood loss was 200 mL (150-300) and the postoperative hospital stay was 1 day (1-1). Transfusion rate was only 1.4%. Intraoperative complications rate was 3.8%. There was a total of 32 (3.1%) major post-operative complications (Clavien III-IV) and 138 (13.3%) minor complications (Clavien I-II). 630 patients were staged pT2 (64.2%) with a positive surgical margin (PSM) rate of 15.7% (99). 349 patients were staged pT3 (35.6%), of which 39.0% (136) had a PSM. 1 patient was staged pT4. Urinary continence (defined as 0 pads/day) returned at 3, 6, 12 and 24 months for 71.9%, 82.1%, 88.5% and 91.2% of patients, respectively. Potency rates (defined as successful penetration) was 25.3%, 32.0%, 43.5% and 50.1% at 3, 6, 12 and 24 months, respectively. Biochemical recurrence occurred in 114 patients (11.0%). 46 patients (4.4%) had hormonotherapy while 136 patients (13.2%) were referred for salvage radiotherapy. CONCLUSIONS This updated study shows comparable results to other high-volume centers. RARP appears to be safe with acceptable surgical, oncological and functional outcomes. © 2018FiguresReferencesRelatedDetails Volume 199Issue 4SApril 2018Page: e46 Advertisement Copyright & Permissions© 2018MetricsAuthor Information Côme Tholomier More articles by this author Félix Couture More articles by this author Marc Zanaty More articles by this author Khaled Ajib More articles by this author Assaad El-Hakim More articles by this author Kevin C. Zorn More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,004 | 0,015 |
| Méta-épidémiologie (sens strict) | 0,001 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,001 |
| Bibliométrie | 0,005 | 0,008 |
| Études des sciences et des technologies | 0,002 | 0,001 |
| Communication savante | 0,002 | 0,001 |
| Science ouverte | 0,002 | 0,002 |
| Intégrité de la recherche | 0,001 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,011 | 0,003 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».