103 Randomized Controlled Trial of the Immediate and Long-term Effect of Massage on Adult Postburn Scar
Notice bibliographique
Résumé
One objective of massage applied to hypertrophic scar (HSc), is to improve the structural properties so skin possesses the strength and elasticity required for normal mobility. However, research supporting this effect is lacking. We therefore conducted a prospective, randomized, single-blinded clinical trial evaluating the impact of a 12 week course of massage. The aim was to characterize the changes in scar elasticity, erythema, melanin, and thickness immediately after massage and after an extended course of treatment compared to matched control scars. Seventy burn survivors consented to participate and 60 completed the study. Two homogeneous, intra-individual scars were randomized to standard of care control (CS) or massage (MS). OTs or PTs provided massage treatment (Tx) 3 x/week for 12 weeks. Scar sites were evaluated weekly immediately before and after massage Tx. The Cutometer, Mexameter, and high-frequency ultrasound were used to evaluate elasticity, erythema, melanin, and thickness respectively. Paired t-tests were used to investigate the immediate changes within each group at each time point. ANCOVAs were performed to test for the immediate and long-term difference between groups. A mixed-model approach was used to account for the intra-individual scars. Tests were two-sided at a significance level of 0.05. There were immediate changes for all scar characteristics except thickness: MS elasticity increased for the first 4 weeks, reaching significance at week 4; MS erythema increased for the first 7 weeks, reaching significance at week 1, 2 & 6 and CS increased for the final 3 weeks, reaching significance at week 10 & 12; MS melanin reduced at each time point, reaching significance at week 1, 2, 5–8, 10 & 11. There was a significant increase in elasticity, and a reduction in thickness, during the 12 week Tx period for both the CS and MS. The increase in elasticity reached significance by week 8 and the reduction in thickness by week 5. There was no significant long-term difference for either erythema or melanin. There was no immediate or long-term group effect of massage for any of the scar characteristics except melanin. The immediate impact of forces applied during massage may mobilize the interstitial fluid associated with the glycosaminoglycans, increase the scar circulation, and exfoliate the scar thereby reducing melanin. However, once baseline measures, the control, and time were incorporated in the analysis there was no immediate or long-term benefit. Ostensible immediate HSc changes after massage do not culminate in long-term improvements in elasticity, erythema, melanin or thickness. Massage applied with the aim to have a long-term impact on these scar characteristics should be reconsidered.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,006 | 0,004 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,002 | 0,001 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,001 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».