Blood Glucose Response during Exercise in the Heat in Adults with Type 1 diabetes
Notice bibliographique
Résumé
Decreases in blood glucose levels during aerobic exercise are a major concern for individuals with type 1 diabetes (T1D), especially if levels drop below the normal range (hypoglycemia). However, the extent to which blood glucose may decline during a given intensity of aerobic exercise in the heat is unclear. Therefore, we examined the changes in blood glucose in individuals with T1D during intermittent exercise in the heat performed at progressively greater exercise intensities. Fifteen, physically active (VO 2peak of 44.7 ± 5.5 mL·kg −1 ·min −1 ) adults (28 ± 6 years) with T1D (hemoglobin A1c: 7.7 ± 1.1%, duration of diabetes: 13 ± 7 years) participated in the study. The participants were permitted to eat a light meal of their choice at least 90 min prior to the start of the experimental trial. Following instrumentation, participants entered a temperature controlled chamber maintained at 35°C where they rested for 30 min. Thereafter they were required to perform three successive 30 min bouts of semi‐recumbent cycling at Light (~35% of VO 2peak ), Moderate (~52% of VO 2peak ) and High intensity (~65% of VO 2peak ) levels. Each exercise bout was followed by a 30‐min recovery. Core body temperature was measured continuously. Blood glucose concentrations were measured every 15 min throughout the entire protocol. Participants ingested glucose tablets as required if blood glucose fell below pre‐specified levels. Core temperature increased gradually above baseline resting (37.10 ± 0.28°C) by 0.35± 0.28°C, 0.62± 0.28°C and 1.04± 0.34°C at the end of Light, Moderate and High intensity exercise bouts, respectively. Baseline resting glucose was 11.17 ± 3.16 mmol·L −1 and remained relatively unchanged throughout each exercise/recovery transition with the exception that blood glucose was reduced (p<0.05) during the High intensity exercise bout (7.38 ± 2.32 and 7.55 ± 3.04 mmol·L −1 at 15‐ and 30‐min of exercise) relative to the prior recovery period (9.65 ± 3.36 mmol·L −1 as measured at 30‐min of recovery) following the Moderate intensity exercise (9.05 ± 3.53 and 8.47 ± 3.71 mmol·L −1 at 15‐ and 30‐min of exercise). Finally, no changes in blood glucose occurred in the last recovery cycle following the High intensity exercise bout (7.33 ± 2.18 and 8.10 ± 2.80 mmol·L −1 at 15‐ and 30‐min of recovery). Eleven of the fifteen participants required glucose supplementation. Two out of the fifteen participants developed hypoglycemia (blood glucose <4.0 mmol·L −1 ). For one participant this occurred in the early stages of recovery following the Moderate intensity exercise (subsequently took 20 grams of glucose tabs) whereas for the second it occurred during both Moderate (subsequently ingesting 12 grams of glucose tabs) and High intensity exercise (subsequently ingesting 20 grams of glucose tabs) bouts. In conclusion, individuals with T1D performing prolonged exercise in the heat are likely to require glucose supplementation to reduce the risk of hypoglycemia, especially at higher work intensities. Support or Funding Information Funding support provided by the Canadian Institutes of Health Research (grant no. 286363, funds held by Dr. Glen P. Kenny)
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,001 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,001 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».