Notice bibliographique
Résumé
Background: as a result of global population aging the amount of aged patients with bipolar disorder (BD) is gradually growing both with the disease onset in the first half of life and with disease onset after 60 years. Aim of the study was to observe clinical features and course of BD in elderly. Material and methods: continuous sample of bipolar in-patients of geriatric clinical units of MHRC aged 60 and older (n = 146) in 2014–2017 were included to comparative study. According to the aim and tasks of the study the patients were divided into 3 groups depending on the age of BD onset: with early-onset BD (0–49 years), new onset in the involution period (50–59 years) and with late-onset BD (60 years and older). All of the patients were examined by psychopathological, clinical and psychometrical method (Hamilton Depression Rating Scale — HAM-D, Hamilton Anxiety Rating Scale — HARS, Young Mania Rating Scale — YMRS, Mini-Mental State Examination — MMSE and Montreal Cognitive Assessment — MoCA). Results: early-onset BD (0–49 years) occurred in 92 patients (63%), new-onset BD in involution period (50–59 years) — in 35 cases (24%), late-onset BD (60 years and older) — in 19 patients included to the study (13%). Early-onset BD was more common in men, while new onset in the involution period — in women. Late-onset BD occurred in men and women with equal frequency. In the majority of patients BD started with depressive episode. Mixed affective episodes showed to be more common as a first BD episode with the increase of disease onset age. Age features of clinical course of affective episodes, cognitive functioningand premorbid characteristics of enrolled patients were viewed and discussed in the study. Early-onset BD leads to more frequent affective episode formation in elderly up to rapid cycling forms, while late-onset BD leads to more prolonged clinical course of affective episodes in comparison with early-onset BD. Premorbid features occur more often in patients with disease onset in thefirst half of life than in patients with late-onset BD. Cognitive functioning of all observed patients stay under age norm during intermission. Conclusion: BD can have its onset at every age, even after 60 years, though in the majority of patients BD onsets before 50 years. Due to ageing, regardless to the age of disease onset depressions and manias in all elderly patients get age-related patterns, mixed affective states become more common.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».