Enregistrement W3005642772 · doi:10.1002/bjs.11468

Therapeutic mammaplasty is a safe and effective alternative to mastectomy with or without immediate breast reconstruction

2020· article· en· W3005642772 sur OpenAlexfundno aff

Shelley Potter, Adam Trickey, Tim Rattay, Rachel O’Connell, Rajiv Dave, Elizabeth A. Baker, Lisa Whisker, Joanna Skillman, Matthew Gardiner, R. Douglas Macmillan, Chris Holcombe, Nicola Barnes, Jane Blazeby, Elizabeth J. Conroy, Adrian Harnett, Paula Williamson, Rajgopal Achuthan, Shweta Aggarwal, Naren Basu, Lisa Brock, Patricia Fairbrother, Charlotte Ives, Abhilash Jain, Baek Kim, John Murphy, Dionysios-Dennis Remoundos, Richard Sutton, Philip Turton, Kathryn Williams, Alain Curnier, Amir Tadros, Ivan Depasquale, Mairi Fuller, Roger Bourne, Steven D. Heys, Ishrak Hamo, Fatima Aloraifi, Laura Fopp, Radhika Bali, Sarah E. Bache, Sarah Benyon, Michael S. Irwin, Amit Agrawal, Charles M. Malata, Claire Murphy, Adam T. Misky, Dennis Wayne Chicken, Nassreen Abdullah, Arnold D. Hill, Carolyn Cullinane, Gareth Irwin, Stuart McIntosh, Sigi Refsum, Samantha Sloan, Peter Mallon, Chiara Sirianni, Ilyas Khattak, Geerthan Nagachandra, Pasupathy Kiruparan, Debasish Debanth, Simon Davey, Terry‐Ann Curran, Matilda Svenning, Sasirekha Govindarajulu, Zenon Rayter, Rachel Ainsworth, Simon Cawthorn, Ajay Sahu, S.W. Wilson, Elena Prousskaia, Antonello Accurso, Nicola Rocco, Rosa Di Micco, Gennaro Limite, Raffaele Ceccarino, Raffaele Liccardo, Guido Coco, Metin Nizamoglu, Mary Morgan, Venkat M. Ramakrishnan, Giuseppe Catanuto, Alex Wilkins, Penelope McManus, Peter Kneeshaw, Kartikae Grover, Tapan Mahapatra, Brendan Wooler, B Eyn Elahi, Naila Bint Ihsan, Alexandra Bucknor, Dimitris Reissis, Judith Hunter, Simon Wood, Navid Jallali, Francis P. Henry, Liaquat Suleman Verjee, Jason Lee, Shazia M Khan, Iman Azmy, Julia Massey, Ciaran Hollywood, Michael Oluwajana, Sonia Bathla, Joanna Seward, Claudia Harding-Mackean, Risha Lane, Kothandaraman Murali, Bashishta Biswas, Pawel Trapszo, Seema Seetharam, Katy Kennedy, Louise Alder, T. Graja, Khalid Amin, Jalal Kokan, Chandeena Roshanlall, Emma Gill, Dhananjay Kulkarni, J. Michael Dixon, Oliver Young, Talha Saleem, Martha Biddle, Marie Kearns, Eva Weiler-Mithoff, Ben Chew, Andy Malyon, John Scott, David J. McGill, Iain R. Mackay, Salena Bains, Sara Barrows, Simon Pilgrim, Sheila Shokuhi, Kelly Lambert, F.S. Kenny, Kalliope Valassiadou, Monika Kaushik, Jarosław Krupa, Pavlos Lampropoulos, S Moss, Haitham Khalil, Anwar Ul Haq, Balapathiran Balasubramanian, Petros Charalampoudis, Hisham Hamed, Ashutosh Kothari, Tibor Kovács, Michael Douek, Iftikhar Mehmood, Biswajit Ray, Matthew Adelekan, Laura Humphreys, Salim Tayeh, Christina Choy, Laila Parvanta, Silvia Michieletto, Tania Saibene, James E. O’Brien, Sue Down, Sarah Downey, Jerome Pereira, Amtul Salam Sami, A Gvaramadze, Jibril A Jibril, Dinesh Thekkinkattil, Sujatha Udayasankar, Saira Khawaja, Yousef Shariaha, Simon Holt, Ruth M. James, Hirah Rizki, Katharine Kirkpatrick, Duraisamy Ravichandran, Deepak Shrestha, Ellora Barua, Deepika Akolekar, Ahmed Hamad, Eleftheria Kleidi, S. Hignett, Vanessa Pope, Salma Naseem, Jennifer Isherwood, Rachel Soulsby, Amanda Taylor, Kian Chin, Dai Nguyen, Francesca Guest, Amanda Thorne, Valentina Lefemine, Chris Kirchhoff, Declan C. Murphy, Michelle Lo, R. B. Harcourt, Simon Pain, Maged Hussien, Katalin Zechmeister, E.M. Sassoon, Andrea Figus, Richard M. Haywood, Rozina Ali, Susanna Alexander, K. Geropantas, Daniel Epurescu, Rebecca L. Lewis, Oladapo Fafemi, Jasdeep Gahir, Tasha Gandamihardja, Jennett Kelsall, Nazli Muhibullah, Charlene Otieno, Fayyaz Mazari, Marta D’Auria, Douglas Macmillan, Eleanor Gutteridge, Tuabin Rasheed, Hazem Khout, Kristjan Asgeirsson, Stephen J. McCulley, Maria Donatella Mariniello, Manuela Roncella, Matteo Ghilli, Livio Colizzi, Elena Rossetti, Lo Russo Marzia, L. Fustaino, Alessandro Quattrini Li, Rebecca C. Windle, Pankaj G. Roy, Gael MacLean, Asha Adwani, Elena G. Popa, Steven Goh, Geeta Shetty, Sarah E. Clark, Lorenzo Bernaudo, Lucy Mansfield, Sally Tebbal, Ashraf Patel, Veronica Grassi, Ojas Pujji, Kathryn Hamnett, Emily Granger, Michael Durbar, Panagiotis Pikoulas, Clare Garnsey, P.L. Walker, Angela J Vollermere, Ioannis Michalakis, Robin M. Jones, Mina Youssef, Mohammad Masood, Julie Dunn, Sisse Olsen, Douglas Ferguson, Rachel Tillett, A. Allan, Alexander Woollard, Rebecca Canny, Afshin Mosahebi, Stephen F. Hamilton, Jagdeep S. Chana, Nilesh M. Sojitra, Ibby Younis, Dick Rainsbury, Natalie Chand, Vasileios Kalles, Anne Stebbing, Kevin M. Harris, Siobhan Laws, Anne Tansley, Geraldine M. Mitchell, Emma de Sousa, Julia Henderson, M. Chandrashekar, Bernadette Pereira, Chloe Constantinou, Dalia Elfadl, Foivos Irakleidis, Izaro Hernan, Miriam Byrne, Jennifer Rusby, Peter Barry, Katerine Krupa, William Allum, Fiona MacNeill, Nicola Roche, Gerald Gui, Kelvin Ramsey, Paul G. Harris, Stuart James, Jamie McIntosh, Nicola Laurence, Louise MacLennan, Robert A. 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Wilson, Sylvia Okwemba, Yousef Majeed, Ciara O’Brien, Vinod Mathen, Ashu Gandhi, James Harvey, Cliona Kirwan, Richard S. Johnson, Krupali Patel, Maria Dalmau I Ribas, Natali Vigneswaran, Tom Challoner, Alan Park, Maged Rizkalla, Abigail Tomlins, Kat McEvoy, Sadaf Jafferbhoy, Soni Soumian, Sankaran Narayanan, Robert Kirby, Sladana Bajrusevic, Joseph Maalo, M Charalambous, Lee Min Lai, K Chong, Simon Thomson, Sherif Monib, Leena Chagla, Riccardo A. Audisio, Rieka Taghizadeh, Karen James, Maria Callaghan, Shabbir Poonawala, Jonathan N. Lund, Raman Vinayagam, Steven Thrush, Rachel Bright Thomas, Michelle Mullan, Jevan Taylor, Ryo Yoshimura, Tom V. Mathew, Ben Mancey Jones, Kailas Munot, Rana Nasr, Jenny Piper, Deena El-Sharief, Mohammad Z. Mustafa, Caitlin S. MacLeod, Elizabeth Smyth, Nina Saeed, Yazan Masannat, Amir Tan Mohd-Amin, Sam Sloan, Abdulla Ibrahim, Rathi Rathinaezhil, Eiman Khalifa, Alexander Leeper, Jennifer McIlhenny, James Mansell, Keith Ogsto, S Shokuhi, Xiang Wei Jonathan Lee, Asmaa Al‐Allak, Clare Fowler, Eleanore Massey, Fiona Court, Richard Hunt, Sarah Vestey, Mohsen El-Gammal, Arish Noshirwani, Tehera Arif, Fahd Syed, Gazalla Safdar, Mohammed El-Abbar, Fiona J. Hogg, Pauline McGee, Vassilis Pitsinis, Jenny Smith, Sundus Makkiyah, Syed Farrukh Mustafa, Dana Photiou, Ellie Gutteridge, Georgette Oni, K Hallam, Kristjan Asgeirron, Samim Al-zubaidi, James A. Bailey, Alexandra Tenovici, Nikos Chaidos, Oana Predescu, J Rezulski, Tholkifl Abdullah, Veronica Grassi, Adam Talbot, Jagdeep Singh, Amy C. Smith, Angela Volleamere, Sarah Dean, Lashan Peiris, Olivia Sjökvist, Aikaterini Micha, Amy Godden, Katherine Krupa, J. Henton, Ruth Bennett, S Nicholson, Guido Paolini, L. Renzi, Santanelli Di Pompeo, Vitto Ria, Rebecca S. Lewis, Sirwan Hadad, Anup Sharma, Delia Toomey, Dibyesh Banerjee, Sarah Shuk Kay Tang, Tanvir Ahmad, Kate Williams, Mohammed Absar, Nabila Nasir, Igor J. Rychlik, Lynn Darragh, Ruth Johnston, Stephen Kirk, Jacqueline Rees-Lee, Michael Green, Abhishek Sharma, Jia Choong, Zaker Ullah, Ommen Koshy, Tamara Kiernan, Ajay Ashok Bhojwani, Rachel Bright-Thomas, Ged Byrne, Ibrahim Ibrahim, Lyndsey Highton, Owen James Morris, Sumohan Chatterjee, B. Mancey-Jones, D El Sharief, Richard Frame

Notice bibliographique

RevueBritish journal of surgery · 2020

Typearticle

Langueen

DomaineMedicine

ThématiqueBreast Implant and Reconstruction

Établissements canadiensnon disponible

Organismes subventionnairesMedical Research CouncilQueen's UniversityQueen's University BelfastResearch Trainees Coordinating CentreAcademy of Medical SciencesUniversity of BristolDepartment of Health and Social CareAssociation of Breast SurgeryNational Institute for Health and Care ResearchUniversity Hospitals Bristol NHS Foundation Trust

Mots-clésMedicineMastectomyMammaplastyBreast reconstructionSurgeryDemographicsTotal MastectomyBreast cancerGeneral surgeryCancerInternal medicine

DOI10.1002/bjs.11468

Résumé

récupéré en direct d'OpenAlex

BACKGROUND: Therapeutic mammaplasty (TM) may be an alternative to mastectomy, but few well designed studies have evaluated the success of this approach or compared the short-term outcomes of TM with mastectomy with or without immediate breast reconstruction (IBR). Data from the national iBRA-2 and TeaM studies were combined to compare the safety and short-term outcomes of TM and mastectomy with or without IBR. METHODS: The subgroup of patients in the TeaM study who underwent TM to avoid mastectomy were identified, and data on demographics, complications, oncology and adjuvant treatment were compared with those of patients undergoing mastectomy with or without IBR in the iBRA-2 study. The primary outcome was the percentage of successful breast-conserving procedures in the TM group. Secondary outcomes included postoperative complications and time to adjuvant therapy. RESULTS: A total of 2916 patients (TM 376; mastectomy 1532; mastectomy and IBR 1008) were included in the analysis. Patients undergoing TM were more likely to be obese and to have undergone bilateral surgery than those having IBR. However, patients undergoing mastectomy with or without IBR were more likely to experience complications than the TM group (TM: 79, 21·0 per cent; mastectomy: 570, 37·2 per cent; mastectomy and IBR: 359, 35·6 per cent; P < 0·001). Breast conservation was possible in 87·0 per cent of patients who had TM, and TM did not delay adjuvant treatment. CONCLUSION: TM may allow high-risk patients who would not be candidates for IBR to avoid mastectomy safely. Further work is needed to explore the comparative patient-reported and cosmetic outcomes of the different approaches, and to establish long-term oncological safety.

Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.

Comment cette classification a été obtenuedéplier

Prédiction distillée sur la base complète

Imitation des enseignants

Ni prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.

score de la tête « metaresearch » (Codex)0,000

score de la tête « metaresearch » (Gemma)0,000

Version: codex-gemma-dda1882f352aStatut de validation: machine_predicted_unvalidated

Catégories candidatesaucune

Catégories consensuellesaucune

DomaineSignal candidat: aucune · Signal consensuel: aucune

Devis d'étudeSignal candidat: Autre devis · Signal consensuel: aucune

GenreSignal candidat: Empirique · Signal consensuel: Empirique

Score de désaccord entre enseignants0,861

Score d'incertitude au seuil0,459

Scores Codex et Gemma par catégorie

Catégorie	Codex	Gemma
Métarecherche	0,000	0,000
Méta-épidémiologie (sens strict)	0,000	0,000
Méta-épidémiologie (sens large)	0,001	0,000
Bibliométrie	0,000	0,000
Études des sciences et des technologies	0,000	0,000
Communication savante	0,000	0,000
Science ouverte	0,000	0,000
Intégrité de la recherche	0,000	0,000
Charge utile insuffisante (le modèle a refusé de juger)	0,000	0,000

Scores machine (provisoires)

Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.

Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.

Tête enseignante Opus0,023

Tête enseignante GPT0,240

Écart entre enseignants0,218 · la distance entre les deux têtes enseignantes sur ce seul travail

Statut de validationscore_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découle

Classification

machine, non validée

Prédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.

Les modèles n’ont appliqué aucune catégorie : rien dans la taxonomie ne correspondait à ce travail.

Devis d'étudeAutre devis

Domainenon disponible

GenreEmpirique

Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».

En bref

Citations39

Publié2020

Routes d'admission1

Résumé présentoui

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