Multi-component exercise training improves the physical and cognitive function of the elderly with mild cognitive impairment: a six-month randomized controlled trial
Notice bibliographique
Résumé
BACKGROUND: This study explored the effects of multi-component exercise training on the physical and cognitive function of the elderly with mild cognitive impairment (MCI). METHODS: A total of 90 older adults with MCI were chosen from screened volunteers and randomly assigned into 2 groups (n=45), and 84 completed the 6-month follow-up. Participants in the control group received general community health instruction, while the multi-component exercise training performed on the other group. The multi-component exercise training performed on these participants was designed to suit Chinese elderly based on advice from the nursing specialist and sports medicine specialist after the preliminary experiment. The Chinese version Mini-Physical Performance Test (CM-PPT), the Mini-Mental State Examination (MMSE), and the Montreal Cognitive Assessment (MoCA) scores were examined by repeated measures analysis of variance to evaluate the physical and cognitive function of adults with MCI before and at 3 and 6 months after the intervention. The follow-up data collectors were blinded to group allocation. P<0.05 was considered statistically significant. RESULTS: (I) The average score of CM-PPT was increased from 11.36±2.69 to 11.88±2.40 and 12.83±2.19 in 3 and 6 months respectively after intervention, while control group was decreased from 10.79±2.73 to 10.24±2.62 in 3 months and 9.21±2.09 in 6 months. CM-PPT scores with the main intervention effect and the interaction between intervention and time were both statistically significant (P<0.05), indicating that the physical function of participants with MCI were improved after intervention. (II) The average score of MoCA was increased from 21.52±2.05 to 23.48±1.47 (3 months) and 25.19±1.29 (6 months) after intervention, while control group was decreased from 21.14.79±1.97 to 20.21±1.88 and 19.45±2.00 in 3 and 6 months. The score of MMSE showed the same trend with the score of MoCA. The MoCA score with main intervention effect and the MMSE and MoCA scores with the effect of time, the MMSE and MoCA scores with the interaction between the intervention and time were all statistically significant (P<0.05), showing that the cognitive function of participants with MCI was improved by the intervention. CONCLUSIONS: Multi-component exercise training could significantly improve physical function and cognitive function of the elderly with MCI. TRIAL REGISTRATION: Chinese Clinical Trial Registry ChiCTR2100049350.
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Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,002 | 0,002 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,002 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,002 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».