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Enregistrement W4210931643 · doi:10.1016/s2213-8587(21)00349-1

Diabetes mortality and trends before 25 years of age: an analysis of the Global Burden of Disease Study 2019

2022· article· en· W4210931643 sur OpenAlexfundno aff

Notice bibliographique

RevueThe Lancet Diabetes & Endocrinology · 2022
Typearticle
Langueen
DomaineMedicine
ThématiqueDiabetes, Cardiovascular Risks, and Lipoproteins
Établissements canadiensnon disponible
Organismes subventionnairesStanford Cardiovascular Institute, School of Medicine, Stanford UniversityFogarty International CenterResearch Management Centre, International Islamic University MalaysiaCentre for Heart Rhythm Disorders, University of AdelaideRussian Academy of SciencesNational Health and Medical Research CouncilMedical Research CouncilSydney Medical SchoolManchester Biomedical Research CentreSamsungGeorge Institute for Global HealthUniversitas PadjadjaranJahrom University of Medical SciencesUniversity of JeddahUniversiti Sultan Zainal AbidinNational Institute of Diabetes and Digestive and Kidney DiseasesMenzies Institute for Medical ResearchWalailak UniversityUniversität UlmXiamen UniversityPomorski Uniwersytet Medyczny W SzczecinieDivision of Mathematical SciencesUniversitas AirlanggaSoutheast UniversityStudent Research Committee, Tabriz University of Medical SciencesShahjalal University of Science and TechnologyMadras Diabetes Research FoundationUniversity of Health and Allied SciencesUniversitatea de Medicină şi Farmacie "Carol Davila" BucureştiUniversidad Autónoma del Estado de MorelosChina Medical UniversityNational Taiwan Normal UniversityUniversity of TorontoUniversité de GenèveUniversity of Technology SydneyUniversitas IndonesiaUnited Arab Emirates UniversityUniversity Of Nigeria NsukkaShahid Beheshti University of Medical SciencesDirectorate for Biological SciencesGöteborgs UniversitetUniversity Grants CommissionUniversitetet i OsloI.M. Sechenov First Moscow State Medical UniversityBangladesh University of Health SciencesShahrekord University of Medical SciencesKermanshah University of Medical SciencesShahrekord UniversityNational Institutes of HealthChinese University of Hong KongHaramaya UniversityCurtin University of TechnologyUniversiti Sains MalaysiaUniversiti Kebangsaan MalaysiaUniversità degli Studi del Piemonte OrientaleCentro de Investigación Biomédica en Red de Salud MentalUniversity of GondarUniversity of TasmaniaUniversity of WaterlooTehran University of Medical Sciences and Health ServicesUniversiti MalayaSultan Qaboos UniversitySeoul National University HospitalKing Abdulaziz UniversityUniversità degli Studi di MilanoArak University of Medical SciencesKarolinska InstitutetIstituto di Ricerche Farmacologiche Mario Negri - IRCCSNational Heart Foundation of AustraliaInstitució Catalana de Recerca i Estudis AvançatsUppsala UniversitetUniversity of CalcuttaAmerican University of SharjahUniversidad Nacional Autónoma de MéxicoCoordenação de Aperfeiçoamento de Pessoal de Nível SuperiorKuwait UniversityDepartment of Social Services, Australian GovernmentUniversiteit UtrechtNational Natural Science Foundation of ChinaKhalifa University of Science, Technology and ResearchIndian Council of Medical ResearchUniversity College LondonAmity UniversityNorthwell HealthTribhuvan UniversityMashhad University of Medical SciencesMinistarstvo Prosvete, Nauke i Tehnološkog RazvojaAnhui Provincial Key Research and Development PlanAustralian Catholic UniversityImperial College LondonKing's College LondonCentre Hospitalier Universitaire VaudoisSeoul National UniversityUniversity of OxfordChandigarh UniversityTulane UniversityIran University of Medical SciencesNovo Nordisk FondenDepartment of Health and Social CareMcMaster UniversityUniversity of LeicesterAkademiska SjukhusetUniversidade Federal do Rio Grande do SulDeutsches KrebsforschungszentrumHarvard UniversityUniversity of WollongongBabol University of Medical SciencesYork UniversityWashington University in St. LouisMonash UniversitySouth Eastern Sydney Local Health DistrictDipartimento di Medicina e Chirurgia, Università degli Studi di Milano-BicoccaSocial Science Research CouncilTrường Đại học Duy TânBill and Melinda Gates FoundationUniversity of WashingtonConselho Nacional de Desenvolvimento Científico e TecnológicoUniverzita Karlova v PrazeImam Abdulrahman Bin Faisal UniversityUniversity of GeorgiaSamara UniversityJordan University of Science and TechnologyNew Mexico State UniversityU.S. Department of Veterans AffairsDepartment of Global Health and Population, Harvard T.H. Chan School of Public HealthJazan UniversityUniversity of New South WalesDepartment of Biotechnology, Ministry of Science and Technology, IndiaHamad Medical CorporationUniversidade Federal de Juiz de ForaDeakin UniversityHelsingin YliopistoBrigham and Women's HospitalDepartment of Anthropology, University of California, Los AngelesUniversidade de São PauloKrishna Institute Of Medical Sciences Deemed To Be UniversityTufts Medical CenterNational Institute for Health and Care ResearchCharles Sturt UniversityUniversitatea din BucureștiLa Trobe University
Mots-clésBurden of diseaseDiabetes mellitusDisease burdenMEDLINEDiseaseQuality-adjusted life year

Résumé

récupéré en direct d'OpenAlex

Background Diabetes, particularly type 1 diabetes, at younger ages can be a largely preventable cause of death with the correct health care and services. We aimed to evaluate diabetes mortality and trends at ages younger than 25 years globally using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. Methods We used estimates of GBD 2019 to calculate international diabetes mortality at ages younger than 25 years in 1990 and 2019. Data sources for causes of death were obtained from vital registration systems, verbal autopsies, and other surveillance systems for 1990–2019. We estimated death rates for each location using the GBD Cause of Death Ensemble model. We analysed the association of age-standardised death rates per 100 000 population with the Socio-demographic Index (SDI) and a measure of universal health coverage (UHC) and described the variability within SDI quintiles. We present estimates with their 95% uncertainty intervals. Findings In 2019, 16 300 (95% uncertainty interval 14 200 to 18 900) global deaths due to diabetes (type 1 and 2 combined) occurred in people younger than 25 years and 73·7% (68·3 to 77·4) were classified as due to type 1 diabetes. The age-standardised death rate was 0·50 (0·44 to 0·58) per 100 000 population, and 15 900 (97·5%) of these deaths occurred in low to high-middle SDI countries. The rate was 0·13 (0·12 to 0·14) per 100 000 population in the high SDI quintile, 0·60 (0·51 to 0·70) per 100 000 population in the low-middle SDI quintile, and 0·71 (0·60 to 0·86) per 100 000 population in the low SDI quintile. Within SDI quintiles, we observed large variability in rates across countries, in part explained by the extent of UHC ( r 2 =0·62). From 1990 to 2019, age-standardised death rates decreased globally by 17·0% (−28·4 to −2·9) for all diabetes, and by 21·0% (–33·0 to −5·9) when considering only type 1 diabetes. However, the low SDI quintile had the lowest decline for both all diabetes (−13·6% [–28·4 to 3·4]) and for type 1 diabetes (−13·6% [–29·3 to 8·9]). Interpretation Decreasing diabetes mortality at ages younger than 25 years remains an important challenge, especially in low and low-middle SDI countries. Inadequate diagnosis and treatment of diabetes is likely to be major contributor to these early deaths, highlighting the urgent need to provide better access to insulin and basic diabetes education and care. This mortality metric, derived from readily available and frequently updated GBD data, can help to monitor preventable diabetes-related deaths over time globally, aligned with the UN's Sustainable Development Targets, and serve as an indicator of the adequacy of basic diabetes care for type 1 and type 2 diabetes across nations. Funding Bill & Melinda Gates Foundation.

Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.

Comment cette classification a été obtenuedéplier

Prédiction distillée sur la base complète

Imitation des enseignants

Ni prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.

score de la tête « metaresearch » (Codex)0,001
score de la tête « metaresearch » (Gemma)0,000
Version: codex-gemma-dda1882f352aStatut de validation: machine_predicted_unvalidated
Catégories candidatesaucune
Catégories consensuellesaucune
DomaineSignal candidat: aucune · Signal consensuel: aucune
Devis d'étudeSignal candidat: Observationnel · Signal consensuel: Observationnel
GenreSignal candidat: Empirique · Signal consensuel: Empirique
Score de désaccord entre enseignants0,051
Score d'incertitude au seuil0,640

Scores Codex et Gemma par catégorie

CatégorieCodexGemma
Métarecherche0,0010,000
Méta-épidémiologie (sens strict)0,0000,000
Méta-épidémiologie (sens large)0,0010,001
Bibliométrie0,0000,001
Études des sciences et des technologies0,0000,001
Communication savante0,0000,000
Science ouverte0,0010,001
Intégrité de la recherche0,0000,000
Charge utile insuffisante (le modèle a refusé de juger)0,0000,000

Scores machine (provisoires)

Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.

Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.

Tête enseignante Opus0,023
Tête enseignante GPT0,299
Écart entre enseignants0,276 · la distance entre les deux têtes enseignantes sur ce seul travail
Statut de validationscore_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découle

Classification

machine, non validée

Prédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.

Les modèles n’ont appliqué aucune catégorie : rien dans la taxonomie ne correspondait à ce travail.
Devis d'étudeObservationnel
Domainenon disponible
GenreEmpirique

Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».

En bref

Citations133
Publié2022
Routes d'admission1
Résumé présentoui

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