MétaCan
Menu
Retour à la cohorte
Enregistrement W4211215881 · doi:10.1002/0471435139.tox068

Organic Chlorofluoro Hydrocarbons

2001· other· en· W4211215881 sur OpenAlexaboutno aff
George M. Rusch

Notice bibliographique

RevuePatty's Toxicology · 2001
Typeother
Langueen
DomaineEarth and Planetary Sciences
ThématiqueAtmospheric Ozone and Climate
Établissements canadiensnon disponible
Organismes subventionnairesnon disponible
Mots-clésOzone layerMontreal ProtocolOzoneStratosphereEnvironmental chemistryOzone depletionEnvironmental scienceChemistryAtmospheric sciencesOrganic chemistry

Résumé

récupéré en direct d'OpenAlex

Abstract The chlorofluorocarbons (CFCs) were introduced in the 1930s as “safe” replacements for refrigerants such as sulfur dioxide, ammonia, carbon tetrachloride, and chloroform. In World War II, they were used to produce insecticide aerosols to protect the troops in tropical areas against malaria and other insectborne diseases. During the next 40–50 years, the number and type of applications expanded to include foam blowing, precision cleaning, and propellants for medicinal, cosmetic, and general‐purpose aerosols, air conditioning, and refrigeration. These uses eventually resulted in emission of the CFCs into the atmosphere. Because of their low chemical reactivity, they typically have long atmospheric residence times, and as a consequence, they are distributed globally. In 1974 Molina and Rowland hypothesized that, once the CFCs reach the stratosphere, they will undergo breakdown to release chlorine atoms. The chlorine atoms could then react with the stratospheric ozone breaking it down into oxygen. Since the stratospheric ozone absorbed much of the sun's ultraviolet β radiation (UVB), decreased ozone levels would lead to increases in ground‐level UVB. This could affect crop growth and lead to increases in cataracts and nonmelanoma skin cancers. Following reports of a marked drop in column ozone over Antarctica (the “ozone hole”) during the Antarctic winter, in 1987 most of the nations of the world drafted and signed an agreement calling for the phaseout of CFCs. This agreement is known as the Montreal Protocol . Development was initiated on two types of “in‐kind” replacements. The first were the hydrochlorofluorocarbons (HCFCs) and the second were the hydrofluorocarbons (HFCs). Both contain hydrogen and are susceptible to attack by hydroxyl radicals present in the atmosphere. Therefore, they have a shorter atmospheric lifetime and either are not transported to the stratosphere or are transported there only in small amounts. The HCFCs contain chlorine and are still capable of causing ozone depletion, although, since their atmospheric lifetimes are short, their ozone‐depleting potential (ODP) is lower than those associated with the CFCs. The HFCs do not contain chlorine (or bromine, also associated with ozone depletion). They, therefore, do not cause ozone depletion. A ranking scale has been developed using CFC11 as the reference compound, with an assigned value of 1. These values are also presented. A second concern, regarding both CFCs and their replacements, is that they are greenhouse warming gases. They, along with other substances such as carbon dioxide, trap the sun's infrared radiation and convert it to heat. However, they are also good insulating materials, and frequently their use as foam blowing agents in refrigeration equipment can lead to considerable energy savings, reducing carbon dioxide emissions. The greenhouse warming potentials (GWPs) for many of the CFCs, HCFCs, and HFCs are given. Many methods have been developed for atmospheric monitoring of these substances. Because of their widespread use and concerns about their environmental effects and health effects, several reviews have been written on these materials. From the reviews as well as the data presented later in this chapter, it can be seen that many of these chemicals are not highly toxic. Some, in fact, do not show significant signs of toxicity at air exposure levels up to a few percent or even over 5 or 10%. The most typical response seen following overexposure is CNS depression related to the anesthetic properties of many of these chemicals. Also, some have caused hepatotoxicity and occasionally reproductive effects. Each compound is discussed individually. They have been divided into three general areas: chlorofluorocarbons, hydrochlorofluorocarbons, and hydrofluorocarbons.

Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.

Comment cette classification a été obtenuedéplier

Prédiction distillée sur la base complète

Imitation des enseignants

Ni prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.

score de la tête « metaresearch » (Codex)0,000
score de la tête « metaresearch » (Gemma)0,000
Version: codex-gemma-dda1882f352aStatut de validation: machine_predicted_unvalidated
Catégories candidatesMéta-épidémiologie (sens strict), Charge utile insuffisante (le modèle a refusé de juger)
Catégories consensuellesCharge utile insuffisante (le modèle a refusé de juger)
DomaineSignal candidat: aucune · Signal consensuel: aucune
Devis d'étudeSignal candidat: Sans objet · Signal consensuel: Sans objet
GenreSignal candidat: Autre · Signal consensuel: Autre
Score de désaccord entre enseignants0,374
Score d'incertitude au seuil1,000

Scores Codex et Gemma par catégorie

CatégorieCodexGemma
Métarecherche0,0000,000
Méta-épidémiologie (sens strict)0,0000,000
Méta-épidémiologie (sens large)0,0000,000
Bibliométrie0,0000,000
Études des sciences et des technologies0,0000,000
Communication savante0,0000,000
Science ouverte0,0000,000
Intégrité de la recherche0,0010,000
Charge utile insuffisante (le modèle a refusé de juger)0,3860,012

Scores machine (provisoires)

Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.

Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.

Tête enseignante Opus0,011
Tête enseignante GPT0,217
Écart entre enseignants0,205 · la distance entre les deux têtes enseignantes sur ce seul travail
Statut de validationscore_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découle

Classification

machine, non validée

Prédiction automatique; les deux têtes enseignantes s’accordent sur ce qui est montré ici.

Devis d'étudeSans objet
Domainenon disponible
GenreAutre

Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».

En bref

Citations1
Publié2001
Routes d'admission1
Résumé présentoui

Explorer davantage

Même revuePatty's ToxicologyMême sujetAtmospheric Ozone and ClimateTravaux en français237 207