Abstract EP46: Can Middle-Aged Recreational Cyclists Remain In Energy Balance And Weight Stable When Involved In An Extreme Exercise And Energy Expenditure Intervention (4E Study)? Effect On Visceral Adiposity And Features Of Cardiometabolic Risk
Notice bibliographique
Résumé
Introduction: Weight loss is often considered a key target in lifestyle interventions aimed at reducing cardiometabolic risk in people with overweight/obesity. However, evidence suggests that regular endurance exercise can induce a mobilization of visceral fat in the absence of weight loss. Therefore, the objective of the present study was to test the effect of an extreme exercise prescription not aimed at weight loss on visceral adiposity and on indices of cardiometabolic health. Hypothesis: Despite our attempt to keep the cyclists weight stable during the 1-week exercise intervention, a loss of visceral fat would be observed. Methods: Eleven male recreational cyclists, aged 50 to 66 years and asymptomatic for cardiovascular disease, cycled 1144 km (715 miles) over a period of seven consecutive days. During the intervention, body weight and composition were assessed daily by bioelectrical impedance and cyclists’ caloric intake was increased to keep them in energy balance and weight stable. Their cardiometabolic health profile was documented before and after the intervention and included a fasting blood test, a resting hemodynamic profile, anthropometric, body composition and body fat distribution measurements including visceral adiposity assessed by magnetic resonance. A maximal cardiopulmonary exercise test was performed at baseline. During the intervention, energy expenditure was calculated from the caloric equivalents of oxygen consumption for each heart rate value acquired with a heart rate monitor. Prepared foods were provided to participants and their energy intake was closely monitored. Results: Small decreases in body weight (-0.8 kg, P <0.05), BMI (-0.3 kg/m 2 , P <0.05) and fat mass (-1.5 kg, P =0.0005) as well as a trend towards an increase in lean mass (+0.8 kg, P =0.07) were observed. Visceral adiposity (-14.1 mL, P <0.01) and waist circumference (-3.2 cm, P <0.0001) decreased while subcutaneous adiposity remained unchanged (-2.7 mL, NS). Decreases in total cholesterol (-1.17 mmol/L, P <0.001), LDL cholesterol (-0.97 mmol/L, P <0.0001), non-HDL cholesterol (-1.32 mmol/L, P <0.0001), triglycerides (-0.77 mmol/L, P <0.005), glycated hemoglobin (-0.1%, P <0.005), and resting systolic (-9 mmHg, P <0.01) and diastolic (-7 mmHg, P <0.01) blood pressure were noted. Conclusion: This study showed that recreational master cyclists were not able to remain in energy balance when exposed to a very large exercise prescription performed over one week. However, despite trivial changes in body weight and no change in subcutaneous adiposity, a significant reduction in visceral adiposity was observed. This study shows the differential response of subcutaneous vs visceral adiposity to a very large prescription of endurance exercise, and the inability of body weight changes to fully appreciate the effects of endurance exercise on features of cardiometabolic risk.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,002 | 0,002 |
| Méta-épidémiologie (sens strict) | 0,001 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,001 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,001 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,006 | 0,001 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».