This issue of Acta

The cover illustrations show intraocular retinoblastoma before and after intra-arterial chemotherapy as described by Tuncer et al. in Turkey in the electronic part of this issue of Acta. Professor Niels Ehlers passed away this summer. He was one of the great leaders of Nordic ophthalmology and was, for many years, Editor-in-Chief of Acta. We miss him as we celebrate his life and achievements. Toke Bek and Anders Heijl remind us of his life and career. Koenraads et al. in Utrecht review Sturge–Weber syndrome and visual impairment due to glaucoma and diffuse choroidal haemangioma. Granstam et al. in Sweden demonstrate that severe visual impairment has decreased over the last decade in Sweden, probably due to anti-VEGF treatment for wet AMD. Vottonen and Kankaanpaa in Kuopio found monthly bevacizumab injections to be the most cost-effective treatment for wet AMD and monthly ranibizumab least cost-effective. Munch et al. in Denmark suggest that vitamin A may be a risk factor for early AMD. Mulder et al. in the Netherlands explored the pharmacokinetics of dabigatran in human vitreous humour. Brynskov et al. in Denmark describe retinal thickening following gastric bypass surgery in patients with diabetes. Godefrooij et al. in Utrecht found that cross-linking for keratoconus has led to fewer corneal transplants. Fredriksson and Behndig in Umea recommend eccentric small-zone laser ray tracing for improved refraction in keratoconus eyes. Xeroudaki et al. in Linköping report that a heparin-mimicking regenerative agent improves corneal wound healing in rabbits. Pillunat et al. in Dresden found preoperative IOP to predict effect of selective laser trabeculoplasty. Mendez-Hernandez et al. in Spain report similar diagnostic capacity of haemoglobin imaging as structural imaging of optic nerve in glaucoma. Melin et al. in Sweden examined the variability of neuroretinal rim measurements and find them to be suitable for long-term follow-up of patients with glaucoma. Raffa et al. in Sweden and Saudi Arabia found that preterm children have lower macular volume than controls. Nibourg et al. in Groningen state that adhesion-mediating peptides control lens epithelial cell adhesion in pigs. They suggest that this mechanism may be interrupted to prevent capsular opacification. Tuulonen et al. in Tampere suggest administrative procedures to improve productivity in eye clinics. Hansen et al. in Copenhagen describe maculopathy in a child with tuberous sclerosis. The following publications are published electronically and are available on the journal's home page www.actaophtalmologica.com Özyol et al. in Turkey record improved control of IOP fluctuations following cataract surgery in primary angle-closure glaucoma. Yu et al. in China record electrolyte changes in aqueous humour following femtosecond laser capsulotomy. Gozawa et al. in Japan use anterior segment OCT to image conjunctival scarring following trans-scleral phacoemulsification. Khalil and Abdelhakim in Cairo found similar outcomes with trabeculotomy and trabeculectomy in congenital glaucoma. Medina-Trillo et al. in Spain describe gene mutations in congenital glaucoma. Kashiwagi et al. in Japan report significant loss of vision after trabeculectomy with 5-year follow-up. Seifi et al. in Canada and Egypt describe gene mutations in Axenfeld–Rieger syndrome. Inoue et al. in Japan measured reduced blood flow in autosomal dominant optic atrophy. Chen et al. in China found altered corneal biomechanics following LASIK as well as small-incision lenticule extraction. Schuerch et al. in Switzerland confirm that corneal cross-linking stabilizes keratoconus in children. Bikbova and Bikbov in Russia and Japan found better results from standard cross-linking compared with transepithelial iontophoresis-assisted cross-linking. Böhringer et al. in Germany recommend arcuate corneal keratotomies for astigmatism following penetrating keratoplasty. Tan et al. in Singapore report reduced choroidal vascularity in patients with diabetes mellitus. Kubicka-Trzaska et al. in Poland found circulating anti-endothelial cell antibodies in patients receiving intravitreal bevacizumab. Wei et al. in China and USA found similar outcome with sclera buckling as re-vitrectomy for inferior retinal detachment in silicone oil-filled eyes. Takemoto et al. in Japan recorded circulatory disturbance in choroid in patients with Vogt–Koyanagi–Harada disease. Chang et al. in China and Germany describe clinical and histological features of adenomas in ciliary epithelium. Tuncer et al. in Turkey recommend intra-arterial chemotherapy for advanced intraocular retinoblastoma. Lemaitre et al. in France review clinical course of women diagnosed with choroidal melanoma during pregnancy. Zegers in Utrecht reports impartial if slightly positive impression by patients of ophthalmologists’ white coats. Sarny et al. in Graz found no connection between interleukin-23 gene and HLA-B27-associated uveitis. Theelen et al. in Nijmegen report macular fibrosis following pigment-deficient maculopathy. Jonas and Panda-Jonas in Germany describe Bruch's membrane defects and staphyloma in toxoplasmosis. Januschowski et al. in Germany emphasize the conclusion of Mattlach et al. in Acta that canaloplasty is better than trabeculectomy. Grixti et al. in Liverpool found amyloid deposits in lacrimal gland. Ashraf et al. in Egypt suggest that ziv-aflibercept is an inexpensive treatment option for diabetic macular oedema. Li et al. in China examine biometrics in myopia and angle-closure glaucoma. Nielsen et al. in Aarhus recommend agar plates to diagnose bacterial keratitis. Sugiura et al. in Japan found macular telangiectasia to affect visual acuity, contrast sensitivity and induce metamorphopsia. Fadlallah et al. in USA and Lebanon used femtolaser incisions to align toric IOLs. Higham et al. in UK report good 3-year outcome of Ozurdex® for macular oedema in retinal vein occlusion. I hope you enjoy this issue of Acta and find it informative.

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