Notice bibliographique
Résumé
The Committee for Establishment of the Clinical Practice Guideline for the Management of Upper Tract Urothelial Carcinoma and the Japanese Urological Association determined clinical questions of the highest priority with regard to upper tract urothelial carcinoma targeted at physicians involved in its treatment. The committee members carefully selected 16 clinical questions essential for daily clinical practice and grouped them into four major categories: epidemiology, diagnosis, surgery and systemic chemotherapy/other matters. I hope this Guideline, a free article, will help standardize the diagnosis and treatment of upper tract urothelial carcinoma, and improve the treatment outcomes. One of the Review Articles is written by Shioyama et al. (Tosu, Japan) on particle RT for prostate cancer. This article summarized the latest treatment outcomes of particle RT on prostate cancer, as well as physical and radiobiological properties of this treatment for the urologist. In conclusion, proton therapy and carbon ion particle RT are considered to be effective treatment modalities for prostate cancer. Another Review Article describes lower urinary tract symptoms. Nomiya et al. (Koriyama, Japan) discuss chronic bladder ischemia associated with bladder outlet obstruction as a result of benign prostatic enlargement or atherosclerosis, animal models of bladder ischemia and the possible mechanisms for chronic ischemia-induced lower urinary tract symptoms. The authors suggest bladder ischemia and oxidative stress as therapeutic targets for drugs aimed at lower urinary tract symptoms treatment. Adjuvant instillations of bacillus Calmette–Guérin remain the standard treatment for intermediate- and high-risk non-muscle invasive bladder cancer, resulting in a significant reduction in tumor recurrence and progression. Pfister et al. (Rouen, France) carried out a prospective, randomized, multicenter study to assess a new schedule of bacillus Calmette–Guérin maintenance treatment, using one-third of the full dose (27 mg) per instillation at 3 months or 6 months, with a reduction of instillations for each cycle (2 vs 3 instillations, respectively). The authors conclude that one-third dose maintenance bacillus Calmette–Guérin is effective with no impact on tumor recurrence or muscle invasion. Among the Original Articles, six relate to prostate cancer. Using data from the Surveillance, Epidemiology and End Results database, Gandaglia et al. (Montreal, Canada) validated a risk score to select the most optimal candidates for adjuvant RT in a large cohort of prostate cancer patients treated with radical prostatectomy for pT3/4 N0/N1 disease. They were able to conclude that the presence of two or more of the pathological features, including Gleason score 8–10, pT3b/4 and lymph node invasion, might be used to identify patients who benefit from early RT. Although this study has some limitations, such as retrospective setting and absence of postoperative prostate-specific antigen data, it could contribute further evidence for the role of adjuvant RT in the postoperative setting for patients with high-risk prostate cancer. Recurrent urinary tract infections can occur in patients with dysfunctional voiding. Minardi et al. (Ancona, Italy) evaluated the therapeutic effects of α1-adrenoceptor antagonists (using tamsulosin) on recurrent urinary tract infections in women with dysfunctional voiding, with particular regard on lower urinary tract symptoms, and urodynamic and voiding parameters. This prospective randomized study suggests that in women with dysfunctional voiding and recurrent urinary tract infections, tamsulosin associated with uroflowmetry biofeedback could be an effective and safe treatment option for improving urinary symptoms and quality of life. None declared.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,001 | 0,009 |
| Méta-épidémiologie (sens strict) | 0,001 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,001 |
| Bibliométrie | 0,002 | 0,001 |
| Études des sciences et des technologies | 0,002 | 0,001 |
| Communication savante | 0,005 | 0,003 |
| Science ouverte | 0,002 | 0,002 |
| Intégrité de la recherche | 0,005 | 0,004 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,304 | 0,160 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; l’étiquette directe de Gemma et le classifieur distillé Codex s’accordent sur ce qui est montré ici.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».