103 Interactions between occupational exposures to extremely low frequency magnetic field and chemicals for brain tumour risk in the INTEROCC study
Notice bibliographique
Résumé
<h3>Objectives</h3> Brain tumors are a serious, often highly disease with few established risk factors. Although ionizing radiation has been clearly linked with brain tumors, there are a number of other environmental and occupational agents suspected. There may also be interactions between occupational agents for brain tumors however the epidemiological literature is sparse. Only one previous epidemiological study examined potential interactive effects between occupational exposure to extremely low frequency magnetic fields (ELF-MF) and chemical agents with various interactive effects observed. The objective of this paper was to examine the possible joint effects of occupational agents for brain tumors (specifically glioma and meningioma) including occupational ELF-MF and chemicals in the large-scale INTEROCC study. <h3>Methods</h3> The INTEROCC study is formed by seven participating countries (Australia, Canada, France, Germany, Israel, New Zealand, United Kingdom) from the parent INTERPHONE study. Cases of primary brain glioma and meningioma aged at least 20 years were recruited between 2000 and 2004. Detailed occupational history data was collected for jobs held at least six months. Job titles were coded into standard international occupational classifications and estimates of ELF-MF and chemical exposure were assigned based on job exposure matrices. Odds ratios (and 95% confidence intervals) for single and joint occupational exposures were calculated according to a common reference category. Interactions on both the additive and multiplicative scale were assessed. <h3>Results</h3> Data on a total of 3,978 brain tumor cases, including 2,054 gliomas and 1,924 meningiomas, were analysed with 5,601 control subjects. A number of interactions were observed, varying according to exposure time window, exposure metric, and included subjects. Results also varied according to tumour type. <h3>Conclusion</h3> Interactions between occupational agents for brain tumors were observed however further research examining possible joint effects of occupational agents for brain tumours with refined assessments of occupational exposure in other large-scale studies is warranted.
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Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,001 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».