Notice bibliographique
Résumé
This monograph examines in mathematical terms an open question in neuroscience on the function of the cerebellum, a major brain region involved in regulation of the motor systems, speech, emotion, and other cognitive functions of the body. Reasoning from the perspective of control theory, we make a hypothesis that the primary function of the cerebellum is disturbance rejection of exogenous reference and disturbance signals. This brings to the fore the internal model principle of control theory: that any good controller must include a model of its environment. The monograph is structured around a pursuit of the validity of this hypothesis. Given the system level architecture and the measurement structure of the cerebellum, is disturbance rejection mathematically feasible? Second, is a disturbance rejection interpretation consistent with experiments? Specifically we investigate the possibility that the cerebellum provides adaptive internal models of signals generated by the environment. After a brief historical overview of computational theories of cerebellar function and of the relevant parts of control theory in the area of regulator theory, we carry out a more or less chronological review of subjects in control theory that impinge on our investigation. We begin with classical regulator theory with its characteristic features of a known plant and known frequency content of disturbance and reference signals. We then pause to examine classical regulator theory from the perspective of modeling the cerebellum, finding that several aspects are not well suited to this endeavor. Foremost is the unrealistic assumption that the plant and exosystem parameters are apriori known. More subtle issues arise from the fact that classical regulator theory developed in a setting where output and error measurements are regarded as persistent, an assumption not valid in the brain. Next, we review adaptive control theory, organized in terms of error models. The main control theoretic tools appear in Section 5, as a synthesis of classical regulator theory and adaptive control, where we present several adaptive internal model designs. To test our hypothesis on cerebellar function, we apply adaptive internal model designs to several motor systems regulated by the cerebellum. These include the slow eye movement systems: the vestibulo-ocular reflex, gaze holding, smooth pursuit, and the optokinetic system. We also study discrete time behaviors regulated by the cerebellum: the saccadic eye movement system and, more generally, visuomotor adaptation. The results from these modeling studies suggest that an interpretation of cerebellar function in terms of disturbance rejection is compelling, with the potential to provide a unifying framework to explain how the cerebellum can contribute to so many different systems in the body. The monograph concludes with suggestions for future research directions.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».