Notice bibliographique
Résumé
Current Opinion in Lipidology was launched in 1990. It is part of a successful series of review journals whose unique format is designed to provide a systematic and critical assessment of the literature as presented in the many primary journals. The field of lipidology is divided into six sections that are reviewed once a year. Each section is assigned a Section Editor, a leading authority in the area, who identifies the most important topics at that time. Here we are pleased to introduce the Section Editor for this issue. EDITOR Robert A. HegeleRobert A. HegeleRob Hegele is a distinguished University Professor of Medicine and Biochemistry, University of Western Ontario, Canada, and Director of the Lipid Genetics Clinic and the London Regional Genomics Centre in London, Ontario, Canada. He received his MD degree from the University of Toronto in 1981. His specialty training in internal medicine and in endocrinology & metabolism was also in Toronto. His post-doctoral research fellowships were at Rockefeller University, USA, and Howard Hughes Medical Institute, University of Utah, USA. From 1989 to 1997 he was on the Faculty of Medicine at the University of Toronto. In 1997 Dr Hegele joined the Schulich School of Medicine and Dentistry and the Robarts Research Institute at the Western University, in London, Ontario, Canada, where he holds the Jacob J. Wolfe Distinguished Medical Research Chair and the Martha Blackburn Chair in Cardiovascular Research. His lab studies the genetics of lipoprotein metabolism, cardio¬vascular disease and diabetes mellitus. Solely or through collaborations, his lab was first to describe the molecular genetic basis of 20 human diseases. His lab has also defined much of the genetic basis of complex disorders, including hypertriglyceridemia. He has co-authored over 600 peer-reviewed publications and has contributed to national treatment guidelines for dyslipidemia, hypertension and diabetes. He is a practicing endocrinologist and has participated in numerous clinical trials. He has trained numerous physicians and graduate students. SECTION EDITORS Frank M. SacksFrank M. SacksDr Sacks is Professor of Cardiovascular Disease Prevention in the Nutrition Department of Harvard Chan School of Public Health; Professor of Genetics & Complexes Diseases; and Professor of Medicine at Harvard Medical School. Dr Sacks led the panel designing the DASH Study, which crafted a healthful eating pattern and demonstrated that it lowered blood pressure more effectively than any previous dietary treatment. Subsequently Dr Sacks led the DASH-Sodium study, which determined the dose-response effect of dietary sodium on BP. These multi-center National Heart Lung and Blood Institute trials found major beneficial additive effects of low salt and a dietary pattern rich in fruits and vegetables on blood pressure. He also led the seminal PoundsLost trial which showed the percentage of calories from fat or carbohydrate had no effect on long term weight loss. Currently, he is co-investigator of the MIND study, a randomized trial of a diet that combines features of the Mediterranean and DASH diets to preserve cognition in older people, funded by the National Institute on Aging. Dr Sacks's laboratory has studied the role of apolipoproteins in atherogenic lipoprotein metabolism in obesity and hypertriglyceridemia. He authored over 30 research papers on apoC-3 and/or apoE. Recently he discovered that a type of HDL that contains apolipoprotein C-III predicted higher rates of heart disease and diabetes, the opposite to the protective relation for the total HDL; and impaired HDL function in reverse cholesterol transport. Dr Sacks teaches at Harvard School of Public Health as course director for nutritional metabolism and biochemistry. Dr Sacks received the 2011 Research Achievement Award of the American Heart Association for lifetime research accomplishment. Majken K. JensenMajken K. JensenMajken K. Jensen, PhD, is Associate Professor of Nutrition and Epidemiology at Harvard T. H. Chan School of Public Health. Dr Jensen's primary research interests include novel metabolic markers, nutrition, and genetics, in relation to chronic lifestyle diseases. In ongoing collaborations with Dr Frank Sacks, they investigate how the presence of a small proinflammatory protein (apolipoprotein C-III) on HDL particles marks a potentially dysfunctional type of HDL that is not inversely associated with risk of cardiometabolic health, such as IMT, diabetes and cardiovascular disease. Other currently funded work is focused on lipoprotein metabolism and Alzheimer's disease and stroke. Her research predominantly utilizes large-scale observational studies (including the Health Professionals Follow-Up Study, the Nurses’ Health Study, the Danish Diet, Cancer and Health study, the Multi-Ethnic Study of Atherosclerosis, and the Cardiovascular Health Study) where cost-efficient prospective case-control studies are nested within for purpose of measuring novel biomarkers or genome-wide markers. Dr Jensen's research has been published in leading scientific journals and has been recognized with numerous awards. She received the Trudy Bush Fellowship for Cardiovascular Disease Research in Women's Health from the American Heart Association in 2011 and originally came for research studies at Harvard T. H. Chan School of Public Health as a Fulbright scholar. Dr Jensen has published over 80 original research articles and 5 reviews, editorials, and letters.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,008 | 0,062 |
| Méta-épidémiologie (sens strict) | 0,003 | 0,001 |
| Méta-épidémiologie (sens large) | 0,002 | 0,003 |
| Bibliométrie | 0,006 | 0,002 |
| Études des sciences et des technologies | 0,003 | 0,002 |
| Communication savante | 0,008 | 0,005 |
| Science ouverte | 0,003 | 0,003 |
| Intégrité de la recherche | 0,007 | 0,008 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,167 | 0,102 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».