386 Effects of Different Soy Protein Sources on Gut Microbiome Composition and Relationship with Performance in Pigs in Regular Nursery and F4 Enterotoxigenic <i>Escherichia Coli</i> (ETEC) Challenged Conditions
Notice bibliographique
Résumé
Abstract Provisoy, produced by hydro, thermal, and mechanical process using soybean meal (SBM) has been shown to improve both post-weaning pig growth and gut health compared with SBM. It was hypothesized that Provisoy could improve the utilization of both protein and fiber fractions along the gastrointestinal tract of a nursery pig resulting in a more balanced nutrient environment and robust microbiome in the hindgut compared with SBM. A total of 268 weaned pigs (body weight, 6.82 ± 0.85 kg) were allotted to either a regular nursery condition (5 pigs/pen, 10-11 pens/treatment) or subjected to ETEC challenge (3 pigs/pen, 12 pens/treatment, 1 pig per pen was orally gavaged with O149:K91:K88 strain on d 5 post-weaning). Pigs received one of the following diets: SBM, Provisoy or HP300 (soy protein from Hamlet Protein, used as a benchmark). A standard wheat-barley-SBM based diet was used, and test soy products were added to replace SBM in the treatment diets during the first three weeks of nursery program. All diets were isocaloric with the same standardized ileal digestible lysine level in a three-phase (38 days) nursery program. Fecal samples were collected on d 13 or d 14 post-weaning and subjected to DNA extraction and Nanopore shotgun sequencing. Data were center-log-ratio transformed and subjected to statistical analysis. Microbiome composition was affected by dietary treatment (P < 0.01) and challenge (P < 0.05), but their interaction was not significant. In regular nursery condition, both Provisoy and HP300 tended (P < 0.10) to have greater microbiome alpha-diversity compared with SBM, but no difference was observed between these two treatments. Only SBM fed pigs subjected to ETEC challenge had greater (P = 0.02) alpha-diversity compared with their non-challenged counterparts. Compared with the SBM treatment, pigs that received Provisoy in the regular condition had greater abundance of Coprococcus and Dialister, which were positively correlated with greater average daily gain (ADG; r = 0.53, P < 0.01, and r = 0.45, P = 0.01, respectively). Under ETEC challenge, an increase in abundance of Dialister was observed in pigs that received Provisoy treatment with a positive correlation with ADG (r = 0.42, P = 0.01). In conclusion, dietary inclusion of Provisoy or HP300 improved microbiome alpha-diversity compared with SBM. Provisoy helped promote the growth of beneficial bacteria in the hindgut of nursery pigs which were positively correlated with gain.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,001 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».