Abstract 1287: The ACCESS consortium: Advancing childhood cancer experience, science and survivorship in Canada
Notice bibliographique
Résumé
Abstract In Canada, >4,300 children, adolescents and young adults are diagnosed with cancer each year. 1/3 have refractory/metastatic disease or will relapse with an expected 5-year survival rate of <15%. The prognosis for most pediatric cancers has stagnated in the past 30 years and Canada trails the US and Europe in providing accessible clinical trials and improved outcomes. Advocacy for change by patients and families led to a federal government investment of $30M in pediatric cancer research. $23M was allocated to establishing a national pediatric cancer consortium. “ACCESS: advancing childhood cancer experience, science and survivorship” is the new multi-stakeholder network created with a vision that every Canadian child with cancer has access to the latest scientific advances, diagnostic tools, therapies and supportive care leading to better outcomes and quality of life. ACCESS will connect the Canadian pediatric cancer community, build partnerships, leverage research and clinical expertise across cancer types and ages, implement transformative change and create a unified national strategy. To date, >350 clinicians, researchers, policymakers, advocates, people with lived experience (PWLE; patients, families and survivors) and other stakeholders have been engaged, with a goal of representing Canada’s ethno-cultural, socioeconomic and geographic diversity. ACCESS is building partnerships between children, families, professionals, and existing programs to collaborate in coordinated research and knowledge mobilization. The goal is to implement transformative change in the delivery of fair, fast, effective and safe cancer care for all Canadian children. ACCESS has developed a statement of its values that includes patient/survivor and family centred; collaborative; anti-oppressive; innovation and excellence; accountable. Uniquely, ACCESS is an interdisciplinary and inclusive organization that directly engages and collaborates with PWLE at all levels of research and governance. ACCESS is organized into 7 themes that will address gaps, advance research and educate through all phases of the pediatric cancer journey: cancer biology; clinical trials; access to innovative therapies and optimal care; regulation, policy and economics; education and training; ethical, legal, societal implications and implementation science; and psychosocial and survivorship. In addition, there are two cross cutting groups focusing on Knowledge mobilization and Social justice, Indigenization and Inclusion. Collaborations with local, provincial, national and international initiatives are being established through the development of a partnership strategy. Cross-consortium priorities are being implemented, and a data management strategy is in development. The publication of a strategic and sustainability plan for ACCESS is anticipated in 2024. Citation Format: Christine J. Williams, Stephanie A. Grover, Adrienne Co-Dyre, David Malkin, James A. Whitlock, on behalf of the ACCESS consortium. The ACCESS consortium: Advancing childhood cancer experience, science and survivorship in Canada [abstract]. In: Proceedings of the American Association for Cancer Research Annual Meeting 2024; Part 1 (Regular Abstracts); 2024 Apr 5-10; San Diego, CA. Philadelphia (PA): AACR; Cancer Res 2024;84(6_Suppl):Abstract nr 1287.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,006 | 0,008 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,001 |
| Bibliométrie | 0,001 | 0,003 |
| Études des sciences et des technologies | 0,020 | 0,005 |
| Communication savante | 0,008 | 0,002 |
| Science ouverte | 0,003 | 0,010 |
| Intégrité de la recherche | 0,002 | 0,005 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,013 | 0,001 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».