Response to: Szuster-Ciesielska, Letter to the Editor Regarding ‘Autopsy Findings in Cases of Fatal COVID-19 Vaccine-Induced Myocarditis’
Notice bibliographique
Résumé
We appreciate concerns expressed by Szuster-Ciesielska about COVID-19 vaccination playing a role in sudden unexplained deaths reported in athletes after the institution of mandates in Europe. Cadegiani has pointed out that in the setting of COVID-19 vaccine induced myocarditis, a surge of catecholamines may play a role in the initiation of lethal ventricular arrhythmias and cardiac arrest.1 In the absence of an autopsy after unexplained death in a previously healthy player, antecedent COVID-19 vaccination and subclinical myocarditis would be reasonable consideration given the findings reported in our paper,2 and as inferred by the work of Polykretis and McCullough.3 Importantly, Polykretis and McCullough re-analysed the data in response to a letter to the editor: ‘We stratified by age and found 558 athletes were ≤35 years and 139 were over 35 years. Such number of documented events is likely largely underestimated, because of the difficulty to gather data from countries where the script/alphabet is not translatable. Notably, in a 38-years timespan (1966-2004), 1101 athletes under the age of 35 died (~29/year) due to various heart-related conditions, 50% of whom had congenital anatomical heart disease and cardiomyopathies and 10% had atherosclerotic heart disease with early onset. The finding of 697 deaths from 2021 forward [<24 months] is concerning for a secular change and these data suggest a research registry for athletes with sudden unexpected cardiac arrest should be initiated with particular attention to COVID-19 vaccine administration data’.3 In other words, a nearly 10-fold increase in sudden death after rollout of COVID-19 vaccination was observed. The report relied upon a public blog of athlete deaths that required multiple press releases for confirmation death occurred in an active player.4 At this time, there is no scientific registry that collates sudden death reports among vaccinated players, however, our present paper suggests such a registry would be important and valuable to the field. In conclusion, our paper contributes valuable knowledge to the understanding of fatal COVID-19 vaccine-induced myocarditis, adhering to rigorous scientific standards while navigating the challenges of sourcing generalizable observations in a novel and rapidly evolving field. We thank Szuster-Ciesielska for their careful analysis and share their concerns regarding the sharp increase in sudden death among athletes during the period where COVID-19 vaccine mandates were enforced among European sports teams. RH and WM are no longer associated with The Wellness Company. PM receives salary support (modest) or equity (modest) in The Wellness Company, which had no role in the original manuscript or in this correspondence.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,001 | 0,002 |
| Méta-épidémiologie (sens strict) | 0,001 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,001 |
| Bibliométrie | 0,001 | 0,001 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,001 | 0,004 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,001 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».