O15 Epidemiological analysis and overall survival of small bowel cancer in a developing middle eastern country over 18 years
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Notice bibliographique
Résumé
<h3>Introduction</h3> Despite that small bowel malignancies are considered to be uncommon, there is an alarmingly worrisome incline in the incidence over the last 4 decades in developed countries. Accordingly, the identification of the epidemiological characteristics of small bowel cancer in developing countries, such as Jordan, is of paramount significance to enable the introduction of effective measures. <h3>Methods</h3> Data on 427 individuals of different nationalities residing in Jordan who were diagnosed with small bowel cancer during the time period of 2000–2018 was obtained from the Jordan Cancer Registry, the official cancer reporting body in Jordan. Epidemiological statistical analysis, including Kaplan-Meier, was performed to establish the epidemiological features and overall survival of small bowel cancer in Jordan over 18 years. <h3>Results</h3> A total of 427 individuals with a mean age of 55.5 ± 13.9 years old with a prominent male predominance of 61.1% were included in the analysis. It was reported that 11.9% were smokers at the time of diagnosis. Despite that 36.9% of the individuals had small bowel cancer not otherwise specified (NOS), it was identified that the duodenum was the most prevalent location as it was reported in 43% of the individuals, followed by the jejunum (9.2%) and ileum (8.1%). Moderately differentiated tumours were the most prevalent (30.7%), followed by poorly differentiated tumours which were identified in 15.2% of the patients. 15.5% of the individuals had localized disease at the time of diagnosis, whereas 19.9% had widespread disease with distant metastasis. Adenocarcinoma was the most prevalent tumour morphology as it was identified in 53.2% of the patients, followed by gastrointestinal stromal tumours and carcinoid tumours which were identified in 12.9% and 7.5% of the individuals, respectively. A statistically insignificant incline in the crude incidence of small bowel cancer in Jordan over 18 years was evident with a crude incidence estimated effect of 0.006. The overall survival was 82.1%, 73.9%, 64.6%, 55.3%, and 55.3% at 1-year, 2-year, 3-year, 4-year, and 5-year interval, respectively. <h3>Conclusions</h3> Small bowel cancer in Jordan exhibits an earlier onset with a mean age at the time of diagnosis younger than developed countries. Additionally, the overall survival of small bowel cancer in Jordan at 5-year interval is lower in comparison to western countries, and thus mandating prompt intervention.
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Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,001 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découle