Recent highlights from the International Journal of Cardiology heart & Vasculature: Comprehensive management of atrial fibrillation
Notice bibliographique
Résumé
Comprehensive management of atrial fibrillationHerein we provide an update on manuscripts focussing on the comprehensive management of atrial fibrillation (AF) recently published in the International Journal of Cardiology Heart & Vasculature.AF is the most common and complex sustained arrhythmia in men and requires a comprehensive management [1,2].Current treatment options have limited efficacy, largely due to the lack of mechanismbased therapeutic approaches.Although many potential drug targets were identified over the last 20 years [3], there are still many important obstacles in their clinical translation [4,5], with only a few (e.g.SK channels) being successfully translated to the clinical phase of drug development [6,7].The AF better care (ABC) pathway is one management strategy for AF that incorporates anticoagulation, better rhythm control and comorbidity management.Compliance with this management strategy of AF is associated with general improvements in patient outcomes during follow-up [8].Stroke prevention: Stroke risk management among patients with AF has improved between 2011 and 2019; however, there is still scope for further gains as many high-risk patients remain inadequately anticoagulated [9].Better stroke risk assessment by clinicians coupled with addressing practitioner concerns about bleeding risk may improve management of high-risk patients [2].Interestingly, with increasing CHADS2 score, not just the risk of stroke, but also the prevalence of coexisting coronary artery disease increases, which underscores the importance of screening for coexisting coronary artery disease in patients who are at high risk for thromboembolic events [10].Rhythm control: Conceptually, it is logical that maintaining sinus rhythm in patients with AF will permit patients to live longer and better.Accordingly, data from the GARFIELD-AF registry showed that early rhythm control strategy in patients with newly diagnosed nonpermanent AF was associated with a lower risk of all-cause mortality and non-haemorrhagic stroke [11].Recent advances in AF ablation techniques have proved effective in restoring and maintaining sinus rhythm with improved safety profiles.Catheter ablation demonstrated lower rates of atrial tachycardia recurrence over time, as well as a significant reduction in the progression from paroxysmal to persistent AF, with no difference in terms of energy source, complications, and clinical outcomes [12].Newer studies and an updated meta-analysis show a good acute outcomes of two cryoballoon technologies for pulmonary vein isolation [13][14][15][16][17][18].Current randomized clinical trials, including the "Cryoballoon Ablation versus Radiofrequency Ablation in Patients with Persistent Atrial Fibrillation (CRRF-PeAF)", are comparing the traditional thermal energy sources cryo-vs radiofrequency energy for catheter ablation of AF [19].Additionally,
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,001 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,001 | 0,000 |
| Méta-épidémiologie (sens large) | 0,002 | 0,003 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,001 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».