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Enregistrement W4404980086 · doi:10.3389/fpubh.2024.1474554

Detection of polio virus in Gaza's sewage demands immediate action

2024· article· en· W4404980086 sur OpenAlexaff
Tara P. Menon, Kate Zinszer, Samer Abuzerr

Notice bibliographique

RevueFrontiers in Public Health · 2024
Typearticle
Langueen
DomaineHealth Professions
ThématiqueHealth and Conflict Studies
Établissements canadiensUniversité de Montréal
Organismes subventionnairesnon disponible
Mots-clésPoliomyelitisSanitationMedicinePoliomyelitis eradicationOutbreakEnvironmental healthVaccinationPolio VaccinationTransmission (telecommunications)HygienePublic healthPoliovirusVirologyVirusNursing

Résumé

récupéré en direct d'OpenAlex

The recent discovery of type 2 vaccine-derived poliovirus (VDPV2) in sewage water samples from Khan Younis and Deir al Balah in Gaza is a critical public health emergency demanding immediate intervention 1 . This finding exposes thousands of Gazans, particularly those living in densely populated displaced persons' camps, to this highly infectious disease, which can cause severe deformities and paralysis. There is no cure for polio; vaccination is the most effective way to prevent infection and subsequent transmission. The aim of this report is to underscore the urgency of intervention and draw attention from The United Nations Children's Fund (UNICEF), the World Health Organization (WHO), and other international health organizations to prevent a potential outbreak that could jeopardize the global polio eradication program.Gaza's overcrowded living conditions, combined with inadequate sanitation and healthcare facilities, create an ideal environment conducive to the rapid spread of the virus. Such conditions have historically fueled polio outbreaks linked to contaminated water sources. In 2021, Nigeria similarly faced a resurgence of polio due to circulating vaccine-derived poliovirus (cVDPV) in areas with poor sanitation 2 . This reemergence was attributed to low vaccination coverage and inadequate water, sanitation, and hygiene (WASH) infrastructure, which allowed the virus to circulate and mutate 3 .In Gaza, the situation is more severe. In 2022, Gaza had high vaccination coverage-at approximately 99% -with polio nearly being eradicated 1 . However, the escalation of hostilities has led healthcare services to collapse, making comprehensive vaccination campaigns difficult to undertake. Close to 17,000 children have missed routine vaccinations, leaving them vulnerable 4 .The few operating health facilities are only partially functional, and there is a dire shortage of medical supplies and vaccines. Humanitarian efforts, such as those by UNICEF and the WHO, are essential but are hampered by the security situation and access problems.Wars and conflicts create fertile ground for infectious diseases to spread, through the destruction of health infrastructure, contamination of water sources, and the displacement of people. This opens up avenues for outbreaks of many largely preventable diseases, as historically observed in other nations in conflict-Iraq, Syria, and Yemen-with reemergence of polio, cholera, and measles in the wake of vaccination disruption and poor sanitary conditions 5 .Preventing a devastating polio outbreak in Gaza requires immediate, coordinated efforts from global health organizations, governments, and non-profits. The top priority must be improving WASH infrastructure, as inadequate access to clean water and poor sanitation significantly increase the risk of virus transmission. In Gaza, over 1.6 million civilians lack access to clean water, making it difficult to maintain basic hygiene and dramatically increasing the risk of waterborne diseases 6 . Furthermore, intensified surveillance and vaccination efforts should target all children under five years of age and will require support from the international community for vaccine supply and logistical assistance. Cross-border entry of medical supplies and vaccines into Gaza must be made possible against the background of ongoing conflict. Strengthening Gaza's health infrastructure is also important to contain the virus -this includes equipping and training health personnel to effectively screen and isolate polio cases, as well as conducting public awareness campaigns on the importance of vaccination and hygiene practices to prevent polio transmission.The presence of the polio virus in Gaza's sewage is a grave indicator of the region's vulnerability and the urgent need for comprehensive public health interventions. Without swift and decisive action, and the provision of essential aid, a polio outbreak could erupt, leaving the health and lives of Gaza's population hanging in the balance.

Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.

Comment cette classification a été obtenuedéplier

Prédiction distillée sur la base complète

Imitation des enseignants

Ni prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.

score de la tête « metaresearch » (Codex)0,003
score de la tête « metaresearch » (Gemma)0,000
Version: codex-gemma-dda1882f352aStatut de validation: machine_predicted_unvalidated
Catégories candidatesaucune
Catégories consensuellesaucune
DomaineSignal candidat: aucune · Signal consensuel: aucune
Devis d'étudeSignal candidat: Sans objet · Signal consensuel: aucune
GenreSignal candidat: Empirique · Signal consensuel: Empirique
Score de désaccord entre enseignants0,717
Score d'incertitude au seuil0,999

Scores Codex et Gemma par catégorie

CatégorieCodexGemma
Métarecherche0,0030,000
Méta-épidémiologie (sens strict)0,0000,000
Méta-épidémiologie (sens large)0,0010,000
Bibliométrie0,0010,002
Études des sciences et des technologies0,0000,000
Communication savante0,0000,000
Science ouverte0,0000,000
Intégrité de la recherche0,0000,001
Charge utile insuffisante (le modèle a refusé de juger)0,0000,000

Scores machine (provisoires)

Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.

Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.

Tête enseignante Opus0,101
Tête enseignante GPT0,431
Écart entre enseignants0,330 · la distance entre les deux têtes enseignantes sur ce seul travail
Statut de validationscore_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découle

Classification

machine, non validée

Prédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.

Les modèles n’ont appliqué aucune catégorie : rien dans la taxonomie ne correspondait à ce travail.
Devis d'étudeSans objet
Domainenon disponible
GenreEmpirique

Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».

En bref

Citations4
Publié2024
Routes d'admission1
Résumé présentoui

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