Prevalence of osteoporosis in patients with knee osteoarthritis awaiting total knee arthroplasty is similar to that in the general population
Notice bibliographique
Résumé
BACKGROUND: Osteoporosis is common in patients with knee osteoarthritis (KOA) awaiting total knee arthroplasty (TKA) and varies in different regional and ethnic. However, it is unclear whether the prevalence of osteoporosis and osteopenia in these patients is different from that in the general population. This study aims to investigate the prevalence of osteoporosis and osteopenia in both populations to help exploring the relationship between the osteoporosis and osteoarthritis, and to explore whether knee function and radiological assessments of KOA are associated with osteoporosis. METHODS: In total, 249 patients diagnosed with KOA awaiting TKA were investigated in this cross-sectional study. The mean age was 70.9 ± 6.4 years. Bone mineral density (BMD) and T scores at the hip and lumbar spine were used to assess bone status using dual X-ray absorptiometry. A matched cohort from 2448 individuals in the Health Examination Center of our hospital was set as controls by matching sex, age (± 3.0 years) and BMI (± 1.0). The Kellgren-Lawrence grades (K-L grades), mechanical femorotibial angle (mFTA), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score and range of motion (ROM) of the knee were measured to evaluate radiological assessments and knee function in patients awaiting TKA and used to explore the association between KOA and BMD or T score. Prevalence of osteoporosis and osteopenia were investigated in the two cohorts, and inferential statistical analyses were undertaken. The chi-squared test or Fisher's exact test was used for categorical variables while comparisons of scores were examined by ANOVA with/without Bonferroni correction or the Kruskal‒Wallis test. RESULTS: The prevalence of osteoporosis and osteopenia in patients awaiting TKA was 30.5% (76/249) and 44.2% (110/249), respectively. In the matched cohort, 72/249 (28.9%) had osteoporosis, while 98/249 (39.4%) had osteopenia. There was no significant difference in the prevalence of osteoporosis or osteopenia between the two groups (χ2 = 2.603, P = 0.272). mFTA was significantly correlated with BMD and T score (P < 0.05), while no correlation was found between K-L grade, ROM or WOMAC and BMD or T score (P > 0.05). CONCLUSIONS: The prevalence of osteoporosis in patients awaiting TKA was similar to that in the general population. BMD and T score were not correlated with WOMAC score or K-L grade but were correlated with mFTA.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,001 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».