(018) DIMENSIONAL NON-LINEAR ASSOCIATIONS BETWEEN PERSISTENT GENITAL AROUSAL SYMPTOMS, ASSOCIATED DISTRESS, AND SEXUAL FUNCTION IN FEMALES
Notice bibliographique
Résumé
Abstract Introduction Persistent genital arousal/genito-pelvic dysesthesia (PGAD/GPD; henceforth “PGA”) has often been studied as a dichotomous variable, comparing symptomatic vs asymptomatic individuals (e.g., Jackowich, Poirier, & Pukall, 2020). Consequently, little is known about the associations between PGA symptoms and sexual function across a continuum of PGA symptom intensity. Objective The objectives are: (1) test for linear and non-linear associations between PGA symptoms and sexual desire; (2) test for linear and non-linear associations between PGA symptoms and other sexual function variables; and (3) distinguish between PGA symptoms and distress caused by those symptoms when predicting sexual function. Testing for non-linear associations is possible only by treating PGA symptoms as a continuum. Methods A sample of n = 1904 females (M = 30 years, SD = 9.7) completed an online survey on sexual function (Female Sexual Function Index, FSFI), genital pain (1 question), PGA symptoms (Jackowich & Pukall, 2020), and distress associated with PGA symptoms (Jackowich & Pukall, 2020). Analyses tested for linear and quadratic (curvilinear) associations between PGA symptoms and sexual function, and between distress caused by PGA symptoms and sexual function. Results The correlation between PGA symptoms and distress caused by those symptoms was r = .31 (p < .0001, no evidence of a curvilinear association), suggesting that these symptoms are only moderately associated with distress. Groups reporting (a) no genital pain, (b) vulvar pain, (c) vaginal pain, or (d) vulvar and vaginal pain differed in their levels of PGA symptoms (Fig. 1), with vaginal pain appearing to contribute little to the pain-related elevation in PGA symptoms. Analyses testing for linear and non-linear associations between PGA symptoms and FSFI sexual desire found a significant positive association and a negative quadratic (curvilinear) effect (Fig. 2), showing that as PGA symptoms increase so does desire, but that this association reverses at the high end of PGA symptoms. Finally, analyses testing for linear and non-linear associations between PGA symptoms and sexual function (total FSFI), and between distress caused by PGA symptoms and sexual function (total FSFI), showed no significant effects of PGA symptoms, but significant negative linear and curvilinear effects for distress caused by those symptoms (Fig. 3). Negative associations (either linear, curvilinear, or both) between distress and sexual function were observed for all FSFI subscales except the satisfaction subscale. Conclusions This is the first study to document an inverted-u shaped association between PGA symptoms and sexual desire. Moreover, whereas PGA symptoms themselves had a negligible effect on sexual function, distress caused by those symptoms had a consistent negative effect. Clinically, these results suggest that PGA symptoms are not universally a negative experience, and that emphasis should be placed on the consequent distress. However, the distinction between sexual function as defined by the FSFI, and distress about sexual function, may be especially relevant to those experiencing PGA symptoms. Finally, the finding that vulvar pain is associated with PGA symptoms, with vaginal pain contributing little to the increased levels of PGA symptoms, may provide insights to the neural underpinning for some people’s PGA symptoms (refer to Pukall, Jackowich, Mooney, Chamberlain, 2018, for related discussion). Disclosure Any of the authors act as a consultant, employee or shareholder of an industry for: Initiator Pharma; Pelva Health.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,001 | 0,001 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,000 |
| Bibliométrie | 0,000 | 0,001 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».