(058) HYPNOTIC INDUCTION OF ORGASM INCREASES PLASMA PROLACTIN IN WOMEN
Notice bibliographique
Résumé
Abstract Introduction Although sexual orgasm is typically a product of “bottom-up” genitosensory stimulation, it is also controlled by “top-down” processing of excitation and inhibition that controls both the timing of parasympathetic and sympathetic blood flow, and the subjective ability to “let go” into the orgasm when it is imminent. Consistent with this, orgasms activate cortical, limbic, hypothalamic, and brainstem structures, have characteristic pelvic floor muscle signatures and spinal cord activation that characterizes sexual “climax”, and can be rated subjectively in terms of the quality and type of sensory stimulation, affective experience, and the evaluation of pleasure. Orgasms are also accompanied by neurochemical and endocrine changes that characterize ecstatic pleasure, satiety, and refractoriness. Among these correlates is a consistent, orgasm-induced surge of prolactin released from the anterior pituitary into the peripheral bloodstream due to an immediate inhibition of dopamine. Orgasms can also be induced without genital stimulation. People experience orgasms during sleep, with exercise, with particular pelvic floor movements, and during hypnotic suggestion. Some women can have orgasms simply by engaging in imagery and fantasy. Paraplegic men and women also report “phantom” orgasms. This suggests that top-down control of orgasm can be activated on its own, suggesting a kind of “orgasm motor memory”. Objective To examine whether orgasms induced by hypnotic suggestion are “real,” in that they are accompanied by a prolactin surge, and how they are rated afterwards on Subjective, Affective, and Evaluative domains of the Orgasm Rating Scale (ORS; Mah and Binik, 2002). Hypnotic induction of laughter was used as a control condition. Methods Blood was taken before and immediately after each condition in 5 healthy premenopausal women who were susceptible to hypnotic induction and were fully clothed during the inductions. In addition to prolactin, blood plasma was assayed for LH, FSH, and total testosterone. Subjective ratings of the orgasms were made using the ORS, and compared to a separate group of age-matched women who used the ORS to rate orgasms induced by solo masturbation and partnered sex. Results Plasma prolactin increased to an average of 147% of baseline after hypnotic orgasm induction, but decreased to an average of 89% of baseline after hypnotic laughter induction. Changes in LH, FSH, and total T were not significant. Characteristic pelvic floor and abdominal contractions of orgasm were observed. Abdominal contractions were also observed with laughter. Relative to orgasms induced by solo masturbation and partnered sex, hypnotic orgasm induction showed the highest scores on the Subjective and Affective domains of the ORS, but did not differ in the Evaluative domain. Conclusions Hypnotic orgasm induction appears to be real, despite no direct genital stimulation. It is likely induced by top-down motor memory and pelvic floor stimulation of pudendal, hypogastric, and/or pelvic nerves. Hypnotic orgasm induction offers therapeutic intervention for women with orgasm difficulties. Disclosure Any of the authors act as a consultant, employee or shareholder of an industry for: FirmTech Inc. (USA); Kadence Bio (UK); Ovoca Bio/IVIX Corp. (Ireland); Reunion Neuroscience (Canada); SmartBod/Lioness, Inc. (USA); Vella Bioscience (USA).
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Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,003 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».