Association Between Refrigerator Openings and Protein Intake After Hospitalization for Heart Failure Decompensation: Protocol for a Prospective Cohort Pilot Study
Notice bibliographique
Résumé
BACKGROUND: Sarcopenia, characterized by loss of muscle mass, reduced strength, and increasing frailty, is common in older adults and is often the result of underlying diseases such as advanced stages of heart failure (HF). Protein intake is crucial for maintaining muscle mass and strength. However, older adults typically consume less protein compared to younger individuals. It has recently been shown that the time of the first refrigerator opening in the morning, indicated by a door sensor, may be correlated with frailty in older individuals living alone. OBJECTIVE: The aim of this study is to determine whether the time of the first refrigerator opening in the morning can serve as a potential indicator of protein intake in older patients (age ≥70 years) after hospitalization for HF decompensation over a period of 6 months. METHODS: This is a substudy of a prospective interventional cohort study that aims to identify changes in digital biomarkers derived from an ambient sensor system, which may support the early detection of HF decompensation. In this substudy, the frequency and timing of refrigerator door openings in participants' homes will be measured. To assess associations between protein intake and refrigerator openings, dietary intake will be evaluated using 24-hour dietary recalls at 3 different timepoints: at 1, 3, and 6 months after hospital discharge. All 24-hour dietary recalls will be conducted by trained dietitians in face-to-face interviews on weekdays. The primary outcome of this study will be the correlation between protein intake and the time (in minutes after midnight) of the first refrigerator door opening at each of the 3 assessment points. RESULTS: The study is currently in the data collection phase. Recruitment began in February 2024. Data analysis will begin after all data have been collected. As of manuscript submission, 12 patients have been recruited. Results are expected to be published by the end of 2025. CONCLUSIONS: Considering that protein-rich foods are typically stored in the refrigerator, the relationship between frailty and refrigerator usage may be a relevant indicator for nutritional assessment, particularly regarding protein intake. In addition, sarcopenia and frailty may also be linked to protein distribution across meals. This study will explore whether monitoring refrigerator openings can serve as a simple method for identifying increased risk of frailty and sarcopenia. Early detection through such monitoring could facilitate timely interventions and potentially reduce the risk of these conditions. TRIAL REGISTRATION: ClinicalTrials.gov NCT06126848; https://clinicaltrials.gov/study/NCT06126848. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): DERR1-10.2196/66299.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,029 | 0,018 |
| Méta-épidémiologie (sens strict) | 0,004 | 0,003 |
| Méta-épidémiologie (sens large) | 0,006 | 0,005 |
| Bibliométrie | 0,002 | 0,002 |
| Études des sciences et des technologies | 0,005 | 0,002 |
| Communication savante | 0,002 | 0,002 |
| Science ouverte | 0,003 | 0,002 |
| Intégrité de la recherche | 0,005 | 0,005 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,030 | 0,008 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».