Evaluating a Chatbot as a Companion for Patients With Breast Cancer: Collaborative Pilot Study
Notice bibliographique
Résumé
Background: Patients with breast cancer frequently experience significant uncertainty, prompting them to seek detailed, personalized, and reliable medical information to enhance adherence to prescribed treatments, medications, and recommended lifestyle adjustments. Although high-quality information exists within oncology guidelines and patient-oriented resources, the provision of tailored responses to individual patient queries remains challenging, especially for non-English-speaking populations. Objective: This study aims to evaluate the potential of an artificial intelligence-driven chatbot, specifically leveraging ChatGPT (GPT-4; OpenAI) combined with retrieval-augmented generation, to deliver personalized answers to complex breast cancer-related patient questions in German. Methods: We collaborated with one of Germany's largest breast cancer Patient Representation Groups to collect authentic patient inquiries, receiving a total of 118 questions. After initial screening, we selected 104 medical questions, organized into 7 distinct categories: aftercare, bone health, ductal carcinoma in situ, diagnostics, nutrition and supplements, complementary medicine, and therapy. A customized version of GPT-4 was configured with specific system prompts emphasizing empathetic, evidence-based responses and integrated with a comprehensive database comprising guidelines, recommendations, and patient information materials published by recognized German medical societies. To assess chatbot responses, we used 4 evaluation criteria: comprehensibility (clarity from a patient perspective), correctness (accuracy per current medical guidelines), completeness (inclusion of all relevant aspects), and potential harm (risk of undue patient harm or misinformation). Ratings were conducted using a 5-point Likert scale by a breast cancer expert (correctness, completeness, and potential harm) and patient representatives (comprehensibility). Results: The chatbot provided high-quality responses across multiple dimensions. Of the 499 responses evaluated for comprehensibility, 427 (85.6%) were rated as comprehensible. Among the 104 responses assessed for the remaining dimensions, 91 (87.5%) were rated as correct, 72 (69.2%) as complete, and 93 (89.4%) as nonharmful. Reasons for incomplete answers included omission of reimbursement details, updates from recent therapeutic guidelines, or nuanced recommendations regarding endocrine therapy and aftercare schedules. In addition, 6 (5.8%) of the answers were rated as potentially harmful due to outdated or contextually inappropriate recommendations. The chatbot also performed well in the nutrition and bone health categories despite occasionally incomplete document retrieval. Conclusions: Our findings demonstrate that an artificial intelligence-powered chatbot with GPT-4 and retrieval augmentation can effectively provide personalized, linguistically accessible, and largely accurate information to German-speaking patients with breast cancer. This approach holds considerable promise for improving patient-centered communication, empowering patients to make informed decisions. Nonetheless, observed limitations regarding response completeness and potential harm underscore the critical need for ongoing human oversight. Future research and development should prioritize regularly updated databases, advanced retrieval methods to handle complex document structures, multimodal capabilities, and clearly articulated disclaimers emphasizing the necessity of professional medical consultation. Our evaluation, along with the provided set of realistic patient questions, establishes a benchmark for future development and validation of German-language oncology chatbots.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,001 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».