The impact of frailty on cardiac surgery outcomes: an international cohort study
Notice bibliographique
Résumé
Abstract Background/Introduction Frailty, affecting between 20–46% of people presenting for cardiac surgery, is associated with increased mortality, perioperative complications and poorer post-operative quality of life. Due to a previous lack of standardised definition and tool for assessment a stricter evaluation of the impact of frailty on cardiac surgery is considered a research priority. Recently the Clinical Frailty Scale (CFS) was identified as the first line assessment tool of choice in cardiac surgery pre-assessment (1) Purpose To evaluate the impact of frailty, assessed pre-operatively using CFS, on cardiac surgery outcomes using routinely available data from international centres represented within our international network. Methods Centres for participation were sought through our international network. Appropriate governance approvals were obtained according to local procedures. Routine electronic data for pre-operative details, risk factor profile, operative details and outcome data, matched for definitions (or based on country-norms), were extracted for patients undergoing elective coronary artery bypass graft (CABG) surgery, valve surgery or combination between 8th January 2024 and 7th January 2025. Outcome measures include In-hospital mortality, post-operative complications (new neurological dysfunction, return to theatre, infection), intensive care and hospital length of stay and post-operative supported care. Data will be cleaned and analysed locally, and collated for reporting (adhering to RECORD statement) and comparison. Analysis, conducted in SPSS, will include descriptive statistics and outcomes by age, sex and frailty severity. Results Of 17 international healthcare organisations across eight countries represented within our international network in January 2024, 6 (35.3%) assessed frailty routinely in cardiac surgery patients. Of those, one (Ireland) did not use CFS and a further two centres did not collect data electronically (Canada, Sweden). Final analysis will include three centres (Australia, England and Scotland). Overall, >2000 patients will be included, with discharge cut-off for final patients 1-month post-surgery (6th February 2025), thus analysis is still to be undertaken. All data analysis will be completed for presentation at ACNAP2025. Conclusion(s) This contemporary prospective cross-sectional study highlights the lack of routine frailty assessment prior to cardiac surgery, and documentation in the electronic health record, internationally. Completed analysis exploring the impact of frailty (measured using the recently preferred tool, the CFS) on cardiac surgery outcomes, will provide important and novel evidence in the process of identifying and addressing frailty in patients undergoing cardiac surgery.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,006 | 0,001 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,003 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».