DO PAIN CATASTROPHIZING, DEPRESSION, AND MENTAL HEALTH INFLUENCE POSTOPERATIVE OUTCOMES FOLLOWING TOTAL HIP ARTHROPLASTY?
Notice bibliographique
Résumé
Total hip replacement (THR) is the definitive treatment for degenerative conditions of the hip with an excellent track record for success. However, there is emerging evidence that patients with musculoskeletal conditions suffering from concomitant psychological and/or mental health ailments may be predisposed to suboptimal outcomes after surgery. Determining whether psychological and mental health influence outcomes following Total Hip Replacement (THR)—and to what extent—has important prognostic, preventive, and therapeutic implications. In this study, we evaluated the influence of pre-operative pain catastrophizing, depression, and/or mental health on post-operative clinical outcomes following THR. We evaluated outcomes as part of a secondary analysis in a prospective cohort observational study of patients undergoing THR. We employed a multivariable mixed model regression analysis to determine whether pain catastrophizing, depression, or mental health was associated with persistent pain, decreased function, and/or higher risk of revision surgery pre-operatively and up to 5 years post-operatively. A Pain Catastrophizing Scale (PCS) score of 30 or above was pre-defined as the threshold for clinically important pain catastrophizing. Depression and mental health were reported and analyzed as binary categorical variables. We used the ICOAP to measure constant and intermittent hip pain and the WOMAC Physical Function measure to measure physical function. A p value of less than 0.05 was considered as statistically significant. The study cohort consisted of 576 patients who underwent THR (49.3% male; 50.7% female), divided into 189 who screened positive for a psychological, mental health, or pain catastrophizing and 387 who did not. All patients improved substantially following THR, with large significant and clinically important improvements between pre-operative and all post-operative follow up time points for both groups. After adjustment, constant pain scores (ICOAP Constant) were 1.35 (SE 0.18) higher in those with a PCS score >= 30 (p = 30. Female sex was also significantly associated with higher pain scores. Physical function scores (WOMAC PF) were 4.61 (SE 0.53) higher (i.e. worse) in those with PCS > = 30. Younger age at surgery and female sex were also associated with higher WOMAC PF scores (i.e. worse function). History of depression or mental health disorder were not significant in the model. Patients with high levels of pain catastrophizing show large improvements in pain and function following THR. However, these patients have higher levels of pre-operative and post-operative pain and lower physical function following THR. Although the differences are small, pain catastrophizing may be used as one element of a risk stratification model to estimate risk of poor post-operative outcome following THR. Whether targeted interventions to address pain catastrophizing can improve surgical outcome remains to be investigated.
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Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,002 | 0,009 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,001 |
| Bibliométrie | 0,001 | 0,001 |
| Études des sciences et des technologies | 0,000 | 0,001 |
| Communication savante | 0,001 | 0,001 |
| Science ouverte | 0,000 | 0,001 |
| Intégrité de la recherche | 0,001 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,001 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».