Primary and secondary adherence to antihypertensive medications during pregnancy and postpartum
Notice bibliographique
Résumé
• Adherence to antihypertensive medications during pregnancy and postpartum has not been comprehensively studied. • In this electronic health records study, 72.6% patients had primary adherence during pregnancy and 73.4% during postpartum. • Secondary adherence during pregnancy was 63.6% among those with pre-existing hypertension. • Patient and healthcare provider race, blood pressure, obesity, insurance type, and parity were associated with adherence. To examine adherence to antihypertensive medications during pregnancy and postpartum among patients with hypertensive disorders of pregnancy (HDP).. Using electronic health records and healthcare claims data, we examined prenatal care patients aged 16–49 years from a health care system in Minnesota who delivered between 2009–2021, had continuous medical and pharmacy insurance coverage throughout pregnancy and up to 6 weeks postpartum, and had HDP (pre-existing/gestational hypertension, preeclampsia, HELLP syndrome, and eclampsia). Primary outcome was primary adherence to antihypertensives during pregnancy and up to 6 weeks postpartum, separately, defined as filling of first outpatient prescription within 7 days. Secondary outcome was secondary adherence during pregnancy among patients with pre-existing hypertension, defined as proportion of days covered, calculated using prescription fill data. We estimated risk ratios (RR) and 95 % confidence intervals (CIs) to assess associations between patient characteristics and adherence. Among 4,647 eligible patients, 526 (11.3%) and 987 (21.2%) had an outpatient antihypertensive prescription during pregnancy and postpartum, respectively. Primary adherence was observed for 72.6% patients during pregnancy and 73.4% during postpartum. Patients with Black versus White healthcare provider at their first prenatal visit were more likely to have primary adherence during pregnancy (RR 1.22, 95% CI 1.03–1.46) while severe blood pressure was associated with adherence during postpartum (RR 1.26, 95% CI 1.14–1.40). Secondary adherence during pregnancy was 63.6%. Patient race, obesity, health insurance type, and parity were associated with secondary adherence. Approximately 70% of eligible patients had primary adherence but secondary adherence was lower for antihypertensive treatment during pregnancy.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».