Notice bibliographique
Résumé
Dr Dhalla has focused his research to advance knowledge in the area of cardiovascular pathophysiology and therapy of heart disease, and by using innovative approaches, he has identified that remodelling of subcellular organelles plays a critical role in the development of congestive heart failure due to myocardial infarction. His work also resulted in the concept that heart dysfunction in diabetes is due to an imbalance between fatty acid and glucose utilization. Moreover, his work demonstrated that stress-induced heart disease is due to the oxidation of catecholamines and that the oxidized catecholamines are the most sensitive index of the prognosis of heart failure. Research in the area of ischemic heart disease has established the role of oxyradicals and intracellular calcium overload in the genesis of ischemia-reperfusion injury. He has published 670 full-length research papers during his professional career. Dr Dhalla is committed to translating laboratory observations into newer treatments for patient care. On the basis of his research, he has cofounded a public company which has now developed several agents for improving the outcome of ischemic heart disease. The first Centre of Excellence in Heart Research in Canada was set up by the Medical Research Council under his leadership in 1978. These activities flourished into the world-renowned Institute of Cardiovascular Sciences, with more than 125 scientists, students and support staff. He has been the prime moving force in attracting first-rate investigators and developing extraordinary research facilities at the Institute. Dr Dhalla has trained more than 145 scientists who are actively engaged in pursuing their research and academic careers all over the world. He has exceptional talents in inspiring young people to undertake challenges for combating heart disease. He has authored/edited 40 books in the field of cardiovascular science and, thus, has helped in the education of numerous students and specialists around the world. The lifetime efforts of Dr Dhalla in the area of cardiovascular research and education have been recognized in the form of 107 honours and awards from all over the world. In his capacity as Secretary General (for 17 years) and President (for three years), Dr Dhalla promoted the International Society for Heart Research and helped to make it a unique forum for the exchange of scientific information in the world. In his current role as Executive Director of the International Academy of Cardiovascular Sciences for the past 10 years, he devotes considerable energies to promote cardiovascular education. He has organized several international conferences in different parts of the world during the past 30 years. He has willingly given his time and boundless energy to share his wisdom in many countries in every corner of the globe. On March 31, 2006, Dr Naranjan S Dhalla stepped down as Director of the Institute of Cardiovascular Sciences at the St Boniface General Hospital Research Centre in Winnipeg, Manitoba. We all know that Dr Dhalla will never ‘retire’ or even take it easy. Indeed, it is his intent now to devote considerable energy to expanding the activities in the International Academy of Cardiovascular Sciences, as well as continuing his own research and editing the journal Molecular and Cellular Biochemistry. His travel schedule is more extensive than ever in his effort to share his knowledge and encourage young people. On October 12 to 15, 2006, his colleagues and friends will gather in Winnipeg to celebrate Dr Dhalla’s achievements in heart research and recognize his stimulating leadership in the field of experimental cardiology.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,003 | 0,014 |
| Méta-épidémiologie (sens strict) | 0,001 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,001 |
| Bibliométrie | 0,001 | 0,001 |
| Études des sciences et des technologies | 0,001 | 0,001 |
| Communication savante | 0,003 | 0,003 |
| Science ouverte | 0,001 | 0,003 |
| Intégrité de la recherche | 0,002 | 0,007 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,018 | 0,012 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».