Metadata record for the article: NRG Oncology/NSABP B-47 Menstrual History Study: Impact of Adjuvant Chemotherapy with and without Trastuzumab
Notice bibliographique
Résumé
This metadata record provides details of the data supporting the claims of the related article: “NRG Oncology/NSABP B-47 Menstrual History Study: Impact of Adjuvant Chemotherapy with and without Trastuzumab.”The aims of the related study were to assemble an observational cohort of pre/perimenopausal women to evaluate the effect of trastuzumab on treatment-related amenorrhea (TRA) and the associations between TRA and circulating reproductive hormone levels. This data record is associated with an article, which is a secondary publication from the main trial. The primary publication of the main trial is https://doi.org/10.1200/JCO.19.01455.<br><br>Type of data: clinical data; multi-center randomized trial of chemotherapy with and without trastuzumab.Subject of data: Women with an intact uterus; at least one ovary; at least one menstrual period in the past 12 months; no use of current oral contraceptive hormones or other hormone replacement therapy.Sample size: 1,458 women enrolled in this study of whom 1,231 consented to baseline blood samples.Population characteristics: Mean age of participants was 44.1 years. 81.5% were White, 90.5% were Non-hispanic, and 86.1% were estrogen-receptor and/or progesterone-receptor positive.Recruitment: Eligible women were enrolled in the B-47 MH substudy upon random assignment to the parent trial.Date of data collection: Participants enrolled from February 8, 2011 to February 10, 2015; Menstrual history assessed through 36 months of follow-up. Geographic location: Multi-center trial in USA, Canada, and Ireland.Trial registration number: https://clinicaltrials.gov/ct2/show/NCT01275677<br><b>Data access</b>The data generated in this study are gathered in csv format with file name B47MHSubstudy.csv.This data file will be available from the NCTN/NCORP Data Archive repository one year after publication of the related article. This in accordance with the policy of the National Cancer Institute (https://nctn-data-archive.nci.nih.gov/).<br>After the embargo period the data file will be made available to researchers who wish to analyze the data in secondary studies to enhance the public health benefit of the original work. Data access requirements may include (but not be limited to): a research plan and a Data Use Agreement (DUA), with legally binding signatures.<br><b>Corresponding author(s) for this study</b><br>Reena Cecchini (CecchiniR@nrgoncology.org)Patricia Ganz (PGanz@mednet.ucla.edu)<br><b>Study approval</b> This multi-center trial was approved by the National Cancer Institute's Central Institutional Review Board (CIRB) and/or local human investigations committees or institutional review boards at institutions participating in this multi-center trial in accordance with National Cancer Institute policies and procedures, with assurances filed with and approved by the Department of Health and Human Services. Written informed consent was required for participation.<br>
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,001 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,001 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,235 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».