Anhedonia in schizophrenia
Notice bibliographique
Résumé
Objective: Anhedonia, a term first used by Ribot in 1896, is a decreased capacity to experience pleasure. It describes the lack of interest and the withdrawal from all usual and pleasant activities. There are two types of hedonic deficit: physical anhedonia and social anhedonia. Physical anhedonia represents the inability to feel physical pleasures (such as eating, touching and sex), while social anhedonia describes the incapacity to experience interpersonal pleasure (such as being and talking to others). In schizophrenia, anhedonia had differently been considered as a personological trait giving rise to the development of psychosis or as a basic symptom underlying the pathological process. Aim of this study was to examine the psychopathological characteristics of anhedonia in schizophrenic patients and to investigate the clinical relations with negative, positive, disorganized and depressive symptoms. Methods: Sixty schizophrenic subjects (25 inpatients and 35 outpatients) attending the Guastalla's Psychiatric Operative Unit, were assessed using the Scales for Physical and Social Anhedonia (PAS and SAS), the Scales for the Assessment of Positive and Negative Symptoms (SAPS and SANS) and the Calgary Depression Scale for Schizophrenics (CDS). Chapman's Scales (PAS and SAS) are two "true-false" self-report instruments measuring the personological (enduring trait-feature) diminished ability to experience sensory and interpersonal pleasures (such as eating, touching, being with and talking to others, sex, smell and sound). Regarding the (PAS and SAS) cut-offs above which a subject can be classified as "anhedonic", we decided to use those proposed in the French version of Chapman's scales (respectively, ≥ 12 for social anhedonia and ≥ 18 for physical anhedonia) on account of the greater specificity and sensitivity compared to Chapman's original limits. Differently, the SANS "Anhedonia/Asociality" sub-scale must be considered as a symptomatological complex (state-like feature) indicating the individual hedonic deficit in pleasant activities. The statistical analysis of the data was performed in two steps using SPSS 10.0. At first, the schizophrenic sample was dichotomized into "anhedonic" and "normal hedonic" subgroups ("double [PAS/SAS] cut-off"), which were compared on the psychopathological scales using the Mann-Whitney Z test; subsequently, in the total schizophrenic sample, Spearman's correlations and a linear regression analysis were calculated to examine the possible association of psychopathological parameters with Chapman's anhedonia ratings (PAS and SAS total scores) Results: Anhedonia reached highly significant levels only in 45% of the schizophrenic sample (n = 27). This "anhedonic" subgroup was distinguished by high scores in disorganization and negative dimensions [no statistical differences in terms of depression and positive symptoms (hallucinations and delusions) were detected between "anhedonic" and "normal hedonic" groups]. Positive correlations between anhedonia [PAS tot. and SAS tot. (as independent variables)], disorganized and negative symptoms [SANS tot. and "disorganization" SAPS subscales (as dependent variables)] have also been described. Conclusions: In this schizophrenic sample, anhedonia appears to be a predictive factor (psychopathological forerunner) for the development of negative and disorganized forms of schizophrenia ("deficit" or "hebephrenic" subtypes).
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,001 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,000 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,002 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».