Patient-reported symptoms in daily oncology practice
Notice bibliographique
Résumé
The number of patients diagnosed with cancer increases. At the same time cancer patients live longer due to earlier diagnosis and more effective therapies. During the course of their disease, patients experience many disease and/or treatmentrelated symptoms that impact health-related quality of life and daily functioning. Symptoms and their impact can be overlooked and/or underestimated by healthcare professionals. If symptoms remain under-recognized, physical, mental, existential and social functioning is affected and opportunities for diagnosis and management of symptoms may be missed. Patient-reported outcome measurement tools (PROMs) can be used to assess and monitor symptoms and symptom burden. The Utrecht Symptom Diary is a Dutch translation and modified version of the Edmonton Symptom Assessment System (ESAS) which is a worldwide frequently used and validated PROM in cancer patients. In 2003, the USD was developed for daily assessment and monitoring of symptoms of cancer and/or treatment-related physical and mental symptoms. It contains a total of 12 items – lack of appetite, nausea, abnormal stool, dysphagia, dry mouth, pain, sleeping problems, shortness of breath, fatigue, anxiety, depressed mood and overall well-being. Symptoms are scored on a zero-to-ten numeric rating scale (NRS), with higher values indicating increasing intensity. Moreover, patients are invited to add symptoms they experience and are not listed on the USD and are asked to prioritize symptoms which need attention in the patient-doctor-nurse conversation first from their personal perspective. Since 2007 treatment and disease specific modules of the USD have been developed. From 2015 the USD became part of the hospital electronic medical files. Over the last years the USD has been implemented in daily practice in other departments of the UMC Utrecht as well as in other (university)hospitals, general practices and hospices in the Netherlands. Moreover, use of the USD is recommended by the Netherlands Quality Framework for Palliative Care. This thesis describes the validation of the USD and patient-reported symptoms through the use of the USD in different patient groups and settings. The studies described in this thesis show the validity of the USD on content, criterion and construct level. In collaboration with the patient, the use of the USD gave insight into symptoms and their impact on quality of life. This insight is essential to provide personalized, supportive care during treatment with targeted therapies and immunotherapy in daily oncology practice.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,001 | 0,001 |
| Méta-épidémiologie (sens large) | 0,001 | 0,000 |
| Bibliométrie | 0,003 | 0,002 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,001 |
| Science ouverte | 0,001 | 0,000 |
| Intégrité de la recherche | 0,001 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,001 | 0,004 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; les deux têtes enseignantes s’accordent sur ce qui est montré ici.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».