Rates of reported cases of acute and chronic Hepatitis B infection in the immigrant and non-immigrant populations in Quebec from 1991-2008
Notice bibliographique
Résumé
BackgroundEarly screening and appropriately timed treatment for chronic hepatitis B (HBV) can prevent the development of cirrhosis, end stage liver disease or liver cancer. New infections can be prevented through vaccination. Immigrants have increased mortality from viral hepatitis and liver cancer, most of which is likely due to undetected chronic HBV, as they are not routinely screened before or after arrival in Canada. The aim of this study was to estimate and compare the rates of newly reported cases of acute and chronic HBV among immigrant and Canadian-born populations. MethodsA population-based cohort study of all reported cases of acute and chronic hepatitis B identified in the Quebec reportable disease database (MADO) from 1991-2008 were deterministically linked to the Quebec immigration database (MIDI). Annual cumulative incidence of reported cases of acute and chronic HBV were estimated and stratified by age, sex, and region of origin. Comparative rate ratios in immigrants vs. non-immigrants were calculated. Numerators were derived from the linked database and denominators were estimated from census data. Poisson regression was used to model and compare the trends in change of disease-specific rates over the study period. ResultsFrom 1991 to 2008, a total of 2,750 acute HBV and 14,633 chronic HBV reported cases were identified and linked. Immigrants accounted for only 5.5% (N=151) of acute HBV infections and they were younger than non-immigrants (30.2 vs. 37.7 years, p< .01). Crude annual cumulative incidence rates of reported cases of acute HBV decreased by 12.7% per year in non-immigrants, but only by 4.2% per year in immigrants over the study period. Immigrants accounted for 43% (N=6,306) of chronic HBV reported cases and they were younger and less likely to be male compared to non-immigrants. Immigrants from South East Asia, Sub-Saharan Africa and Eastern Europe/Central Asia had the highest rates of chronic HBV [191.4/100,000 population; 95% CI (189.2, 201.9), 170 (156.8, 181.2) and 44.9 (40.7, 49.2) respectively] with rates ratios ranging from 6.2 (5.6, 6.9) to 26.9 (25.9, 28.1) compared to non-immigrants. Over the study period, crude annual cumulative incidence rates of reported cases of chronic HBV decreased by 7.2% annually in non-immigrants whereas they increased by 1.9% per year in immigrants. ConclusionsIncreasing cumulative incidence rates of reported cases of chronic HBV over the study period in immigrants and very high cumulative incidence rates in certain sub-groups suggest that many immigrants groups could benefit from targeted HBV screening programs.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,001 | 0,002 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,001 | 0,002 |
| Études des sciences et des technologies | 0,001 | 0,000 |
| Communication savante | 0,001 | 0,000 |
| Science ouverte | 0,001 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,003 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».