Особливості і динаміка когнітивних порушень у хворих на первинний і вторинний мозковий ішемічний півкульовий інсульт
Notice bibliographique
Résumé
Acute cerebrovascular disease is a global medical and social problem of the modern angioneurology, occupying leading positions in the structure of morbidity and mortality among adult population of the world. Ischemic stroke – is one of the most common pathology. Today this disease took out the world pandemic. More than 16 million new cases of cerebral infarction recorded in the world each year and it “kills” about 7 million of people.About 111,953 cases of cerebral stroke were registered in 2013 in Ukraine. Cognitive impairment, t hat significantly disrupt daily activities and life of the patient, is one of the most significant post-stroke complications that have social, medical and biological significance.Aim. The purpose of this investigation was to study features and dynamics of cognitive impairments in patients with primary and recurrent cerebral hemispheric ischemic stroke (CHIS ) in the acute stage of the disease.Materials and methods. To achieve the aim, and the decision of tasks in the clinic of nervous diseases Zaporozhye State Medical University (supervisor - Doctor of Medicine, Professor Kozelkin A.) based on the department of acute cerebrovascular disease were performed comparative, prospective cohort study, which included comprehensive clinical and paraclinical examinations of 41 patients (26 men and 15 women) aged 45 to 85 years (mean age 66,4 ± 1,4 years) with acute left-hemispheric (2 patients) and right - hemispheric (39 patients) CHIS . First up was a group of 28 patients (19 men and 9 women, mean age 65,6 ± 1,6 years), who suffered from primary CHIS. The second group consisted of 13 patients (7 men and 6 women, mean age 68,1 ± 2,5 years) with recurrent CHIS. The groups were matched by age, sex, localization of the lesion and the initial level of neurological deficit.All patients underwent physical examination, neurological examination. Dynamic clinical neurological examination assessing the severity of stroke was conducted using a NIHS scale. Neuropsychological examination included verification of the existence and structure of the cognitive impairments using scales Montreal Cognitive Assessment (MoCA), Mini-Menthal State Examination (MMSE), Frontal Assessment Battery (FAB) on the 1st -3rd and 10 - 13th day of the acute period of the disease. Outcome of the acute period of the disease was assessed by the modified Rankin scale .All patients underwent a CT scan (Siemens Somatom Spirit, Germany) of the brain and laboratory investigations. The obtained data were processed using the program Statistica 6.0 (StatSoft., USA ) and software package Microsoft Excel.It was detected that patients with recurrent ischemic supratentorial stroke are characterized with lower summary score by Mini-Menthal State Examination, Montreal Cognitive Assessment and Frontal Assessment Battery scales than those with first stroke episode. It was revealed that moderate cognitive disturbances are prevailed in the structure of cognitive disorders in primary stroke, while in recurrent brain ischemia mild and moderate dementia is dominated. Transitory type of perception-gnostic field violations in primary ischemic supratentorial stroke was established. The leading cognitive domains which are associated with expressed cognitive disfunction in patients with recurrent brain ischemia were detected.Conclusions. The patients with recurrent CHIS were characterized by more severe cognitive impairment in the acute period of the disease, so a primary CHIS we can considered as a main risk factor for the progression of cognitive disorders in a specified group of patients.
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,002 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,001 | 0,000 |
| Bibliométrie | 0,000 | 0,001 |
| Études des sciences et des technologies | 0,001 | 0,001 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,001 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,005 | 0,001 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; les deux têtes enseignantes s’accordent sur ce qui est montré ici.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».