Selective Studies on the Challenges of Cannabis Use in Children, Youth and Young Adults
Notice bibliographique
Résumé
The legalization of medical and recreational cannabis in Canada poses several challenges and opportunities in children, youth, and young adults. A clear understanding of the challenges and opportunities, though, remains elusive as cannabis use in younger people is vastly understudied. An evidence base is growing for use of medical cannabis to treat refractory pediatric seizures and to aid in the management of oncology pain. With some conditions, however, there is no data to support efficacy or safety but public enthusiasm has promoted off-label use. For example, some parents have admitted to administering cannabis for refractory symptom management of their child’s attention deficit hyperactivity disorder (ADHD). Presently, there are no trials on the efficacy or safety of medical cannabis in children, youth, or young adults with ADHD. Dosing recommendations for such studies will require an understanding of the pharmacokinetics of cannabis components in children diagnosed with ADHD or other off-label conditions. Children and youth who are successfully stabilized on medical cannabis have also experienced other challenges. For example, some children who take medical cannabis require a dosage during the school day. School policies that address the risks of recreational cannabis can be prohibitive for those who require cannabis to treat a medical condition. With respect to recreational cannabis, its use in youth is concerning since cannabis can cause harm to the developing brain. Education is needed for youth, their parents, and teachers to promote risk reduction and healthy choices. \n\nThis PhD program explored both medical and recreational aspects of cannabis use in the vulnerable population of children, youth, and young adults. In the context of medical use, the first objective was to determine treatment efficacy and pharmacokinetics of cannabis in ADHD, a pediatric condition where there was a perceived benefit, but lack of evidence. We designed a proof-of-concept study, but experienced significant delays with the Covid-19 global pandemic and challenges with study recruitment. Nevertheless, we published the study protocol and a case report describing our experience and cannabinoid plasma levels in three young adults taking medical cannabis for treatment of their ADHD. The potential challenge of medical cannabis at schools was also examined. A scoping review of the scientific literature, Canadian policies and laws underscored the lack of clear guidance on medical cannabis in schools and discrepancies across jurisdictions. Qualitative studies exploring the experiences of clinicians who authorize medical cannabis for school-aged children and caregivers highlighted challenges for these individuals, and guidance for moving this area forward. To address the use of cannabis in children and youth in a recreational context, we developed an educational toolkit for middle school and high school students, parents, and teachers. This education program was approved as a curriculum resource by the Ministry of Education in Saskatchewan and can be accessed by Saskatchewan teachers. The evolving cannabis legislation in Canada requires effective education and communication, both for reducing the risks associated with recreational cannabis and decreasing the stigma for those who require it medically.
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Comment cette classification a été obtenuedéplier
Prédiction distillée sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Apprise à partir de 10 348 étiquettes directes de Codex et de 10 348 étiquettes directes de Gemma. Le mode candidate est l'union des têtes enseignantes seuillées; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont ni des étiquettes humaines ni des étiquettes directes de modèles de pointe.
Scores Codex et Gemma par catégorie
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,000 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,000 | 0,001 |
| Études des sciences et des technologies | 0,001 | 0,001 |
| Communication savante | 0,000 | 0,001 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,000 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,000 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule tête enseignante, pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».