(079) Predictors of Failed Trial of Void After Rezum Water Vapor Therapy for Benign Prostatic Hyperplasia
Notice bibliographique
Résumé
Abstract Introduction Benign prostatic hyperplasia (BPH) is a common condition that affects a significant portion of men in mid to late adulthood. Rezum water vapor therapy, a minimally invasive intervention that utilizes convective water vapor energy to reduce prostatic tissue volume and alleviate obstruction, has demonstrated favourable safety and efficacy in treating BPH. Post-treatment, patients are discharged with a Foley catheter insertion and undergo a trial of void (TOV) at catheter removal. Failure to void at this time results in re-catheterization, prolonging patient discomfort and increasing the risk of urinary tract infection and other catheter-associated complications. Despite growing data on Rezum water vapor therapy as a treatment for BPH, there is limited data on predictors of post-operative trial of void success. Objective This study aims to identify clinical and procedural variables associated with failed TOV following Rezum therapy, aiming to contribute to the limited literature on outpatient Rezum outcomes. Methods We conducted a retrospective study of patients undergoing Rezum water vapor therapy at a Canadian ambulatory surgical centre from April 2022 to November 2024. Data was collected retrospectively from patients who were over the age of 18, receiving Rezum water vapor therapy, and were not using a Foley catheter prior to the procedure. Baseline characteristics, number of injections, and post-operative progress markers were recorded. Univariate logistic regression analysis for each collected variable was performed to determine predictive factors. Results Among 314 procedures performed from April 2022 to January 2025, the mean patient age was 68.8 ± 8.0 years with mean BMI of 29.3 ± 4.9. Of these patients, 2.9% (n = 9) failed the TOV, while 4.8% (n = 15) were initially able to void but later failed the TOV, and 92.3% (n = 290) successfully voided during the initial TOV. All TOVs were conducted during the 1-week post-operative follow-up. Univariate logistic regression analysis revealed that pre-operative post-void residual volume (PVR) was statistically significant in association with the outcome of the TOV (p = 0.0125). Age, BMI, gland size, median lobe size, total injections, and median lobe injections were not significantly associated with the TOV failure. Conclusions Our findings identify pre-operative PVR as the sole predictor of failed trial of void (TOV) following catheter removal after Rezum water vapor therapy in an outpatient setting. Recognizing patients at increased risk for re-catheterization may facilitate more personalized and effective post-operative care. Ongoing long-term follow-up is necessary to evaluate the durability of surgical outcomes. Disclosure Any of the authors act as a consultant, employee or shareholder of an industry for: Boston Scientific
Récupéré en direct depuis OpenAlex et désinversé. Les résumés ne sont pas conservés dans cette base de données : les index inversés représentent 8,6 Go des 9,3 Go de texte de la base, et le serveur dispose de 13 Go libres.
Comment cette classification a été obtenuedéplier
Prédiction machine sur la base complète
Imitation des enseignantsNi prévalence calibrée, ni vérité terrain. Validation humaine à venir. Le volet Gemma est une étiquette directe du modèle pour chaque travail de la base, lue sur la notice réduite au titre. Le volet Codex est un classifieur appris des 10 348 étiquettes directes de Codex et calibré sur les taux pondérés de l'échantillon; les champs sans appui suffisant ne portent aucun appel Codex. Le mode candidate est l'union des deux volets; le consensus est leur intersection. Ces sorties portent le statut machine_predicted_unvalidated et ne sont pas des étiquettes humaines.
Scores du classifieur distillé par catégorie (deux têtes)
| Catégorie | Codex | Gemma |
|---|---|---|
| Métarecherche | 0,000 | 0,002 |
| Méta-épidémiologie (sens strict) | 0,000 | 0,000 |
| Méta-épidémiologie (sens large) | 0,000 | 0,000 |
| Bibliométrie | 0,001 | 0,001 |
| Études des sciences et des technologies | 0,000 | 0,000 |
| Communication savante | 0,000 | 0,000 |
| Science ouverte | 0,000 | 0,000 |
| Intégrité de la recherche | 0,000 | 0,001 |
| Charge utile insuffisante (le modèle a refusé de juger) | 0,003 | 0,000 |
Scores machine (provisoires)
Les deux têtes enseignantes du modèle étudiant, lues sur ce travail. Un score ordonne la base pour la relecture; il n'affirme jamais une catégorie, et le statut de validation accompagne chaque rangée tel quel.
Scores de référence d'un modèle non mature (critères de maturité non atteints, 7 itérations). Un score ordonne; il n'affirme jamais une catégorie.
score_only:v0-immature-baseline · tel quel depuis la passe de notation : score_only signifie que le nombre peut ordonner les travaux, et qu'aucune étiquette de catégorie n'en découleClassification
machine, non validéePrédiction automatique; un appel candidat d’une seule source (Gemma direct ou Codex distillé), pas un consensus.
Le détail, modèle par modèle et score par score, se trouve en fin de page sous « Comment cette classification a été obtenue ».